RSC2 Antibody
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中文名稱:RSC2兔多克隆抗體
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貨號(hào):CSB-PA312369XA01SVG
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規(guī)格:¥880
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RSC2 Antibody Polyclonal antibody
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Uniprot No.:
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基因名:RSC2 Antibody
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別名:Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2) RSC2 YLR357W L9638.1
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宿主:Rabbit
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反應(yīng)種屬:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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免疫原:Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RSC2 protein (401-641aa)
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免疫原種屬:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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標(biāo)記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is involved in meiotic sporulation through regulating IME2 expression, and is also essential for 2-micron plasmid maintenance and for normal REP1 protein localization.
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基因功能參考文獻(xiàn):
- Results show that H4 acetylation by the NuA4 complex and RSC2 are both required for gap-induced sister chromatid recombination. PMID: 25132173
- This study uncovered a direct interaction between the Rsc2 BAH domain and histone H3 and led to the identification of an interaction interface that is conserved in a subset of Rsc-like BAH domains. PMID: 23907388
- Data show that RSC1 and RSC2 are haploinsufficient for spore formation in a smk1 hypomorph. PMID: 15302824
- RSC2 may function through the tRNA element to restric the spread of silencing PMID: 16079223
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亞細(xì)胞定位:Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
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蛋白家族:RSC1 family
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數(shù)據(jù)庫鏈接:
KEGG: sce:YLR357W
STRING: 4932.YLR357W
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