prn Antibody
產(chǎn)品詳情
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產(chǎn)品描述:
The CSB-PA321224LA01BUA polyclonal antibody against prn was generated in rabbits through immunization with the recombinant Bordetella pertussis Pertactin autotransporter protein (632-910aa). The prn protein is an agglutinogen that binds to eukaryotic cells, facilitated by the R-G-D sequence, and is potentially involved in bacterial adhesion, contributing to the virulence of the organism. It is synthesized only in the presence of low Mg2+ concentration and may play a role in the development of whooping cough.
The purified rabbit anti-Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) prn polyclonal antibody exhibited a 95% purity level following protein G purification. This non-conjugated IgG specifically reacts with the prn proteins of Bordetella pertussis origin and is suitable for detecting endogenous levels of prn protein, as tested in ELISA.
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產(chǎn)品名稱:Rabbit anti-Bordetella pertussis prn Polyclonal antibody
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Uniprot No.:
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基因名:prn
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別名:prn antibody; omp69A antibody; BP1054 antibody; Pertactin autotransporter antibody; P.93) [Cleaved into: Outer membrane protein P.69; Pertactin translocator] antibody
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宿主:Rabbit
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反應(yīng)種屬:Bordetella pertussis
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免疫原:Recombinant Bordetella pertussis Pertactin autotransporter protein (632-910AA)
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免疫原種屬:Bordetella pertussis
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,prn Antibody (CSB-PA321224LA01BUA),的標(biāo)記方式是Non-conjugated。對于prn Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough.
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基因功能參考文獻(xiàn):
- Prn-KO strains induced an increased production of pro-inflammatory cytokines by human and murine dendritic cell. PMID: 29559630
- Multiple driving forces required for efficient secretion of autotransporter virulence proteins, such as pertactin. PMID: 25670852
- Results indicate that the purified pertactin is a potential candidate as immunogen for preparation of diagnostic reagents and as a vaccine component. PMID: 20306653
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亞細(xì)胞定位:[Pertactin autotransporter]: Periplasm.; [Outer membrane protein P.69]: Secreted. Cell surface.; [Pertactin translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
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數(shù)據(jù)庫鏈接:
KEGG: bpe:BP1054
STRING: 257313.BP1054
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