CDH6
CDH6,即K-鈣黏蛋白,是II型鈣粘蛋白家族的關(guān)鍵成員,其結(jié)構(gòu)包括胞外結(jié)構(gòu)域、跨膜區(qū)和胞內(nèi)尾巴,這種結(jié)構(gòu)賦予它在細(xì)胞黏附和信號(hào)轉(zhuǎn)導(dǎo)中的重要作用。CDH6在多種組織和器官中廣泛表達(dá),尤其在腎臟和膽囊中表達(dá)水平較高,并在多種惡性腫瘤如卵巢癌和腎細(xì)胞癌中觀察到過表達(dá)現(xiàn)象,與腫瘤的發(fā)展和進(jìn)展密切相關(guān)。盡管CDH6的具體信號(hào)通路尚未完全明確,但可以推測(cè)它可能通過與其他細(xì)胞表面分子或細(xì)胞內(nèi)信號(hào)分子相互作用,參與細(xì)胞黏附、遷移、增殖和分化等過程的調(diào)控。此外,CDH6還在企業(yè)級(jí)應(yīng)用中發(fā)揮重要作用,與Apache Hadoop生態(tài)系統(tǒng)中的Ranger結(jié)合,為企業(yè)提供全面的大數(shù)據(jù)解決方案,確保數(shù)據(jù)的安全性和可靠性。然而,關(guān)于CDH6的具體信號(hào)通路和調(diào)控機(jī)制,仍需進(jìn)一步深入研究。
熱銷產(chǎn)品
Recombinant Human Cadherin-6(CDH6),partial (Active)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 2μg/mL can bind Anti-CDH6 recombinant antibody (CSB-RA005055MA1HU),the EC50 is 2.421-2.802 ng/mL.
CDH6 Antibodies
CDH6 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA005055ESR1HU | CDH6 Antibody | Human | ELISA, WB, IHC |
CSB-PA004767 | CDH6 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA038132 | CDH6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA789505 | CDH6 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-RA005055MA1HU | CDH6 Recombinant Monoclonal Antibody | Human, Macaca fascicularis, Rat | ELISA |
CDH6 Proteins
CDH6 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP005055HU1 CSB-EP005055HU1 CSB-BP005055HU1 CSB-EP005055HU1-B |
Recombinant Human Cadherin-6 (CDH6), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-CF005055HU | Recombinant Human Cadherin-6 (CDH6) | in vitro E.coli expression system |
CSB-MP005055HU1 | Recombinant Human Cadherin-6(CDH6),partial (Active) | Mammalian cell |