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CCR9

CCR9具有七個跨膜區(qū)域、兩個胞漿區(qū)域和一個胞外區(qū)域。這種結(jié)構(gòu)使得CCR9能夠與其特定的配體結(jié)合并傳遞信號。其配體為CCL25(也稱為TECK),這是一種由腸上皮細胞產(chǎn)生的趨化因子,能夠吸引CCR9表達的免疫細胞,如T淋巴細胞和巨噬細胞,向腸道遷移。CCR9/CCL25信號通路在腸道免疫調(diào)節(jié)中具有重要作用,特別是在炎癥性腸?。ㄈ缈肆_恩病和潰瘍性結(jié)腸炎)等疾病的發(fā)病機制中。

熱銷產(chǎn)品

Recombinant Human C-C chemokine receptor type 9 (CCR9)-VLPs (Active)

驗證數(shù)據(jù)

HPLC-SEC
CSB-MP004848HU HPLC-SEC

The purity of VLPs was greater than 95% as determined by HPLC-SEC.

WB
CSB-MP004848HU WB

CSB-MP004848HU is detected by Mouse anti-6*His monoclonal antibody.

ELISA
CSB-MP004848HU ELISA

Measured by its binding ability in a functional ELISA. Immobilized Human CCR9 at 10μg/mL can bind Anti-CCR9 recombinant antibody (CSB-RA004848MA1HU),the EC50 is 31.67-36.83 ng/mL.The VLPs (CSB-MP3838) is negative control.


CCR9 Antibodies

CCR9 for Homo sapiens (Human)

CCR9 Proteins

CCR9 Proteins for Homo sapiens (Human)

CCR9 Proteins for Ovis aries (Sheep)

CCR9 Proteins for Mus musculus (Mouse)