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IL2RA

IL2RA,全名為Interleukin-2 Receptor Alpha,又稱CD25(Cluster of Differentiation 25),是一種細胞表面受體,屬于白細胞介素-2(Interleukin-2,IL-2)受體家族。是IL-2受體的α亞單位,在免疫細胞表面廣泛表達,特別是在T淋巴細胞(T細胞)中高表達。IL2RA的高表達與T細胞活化狀態(tài)密切相關(guān),是T細胞應(yīng)答的一個重要標(biāo)志。IL2RA在調(diào)節(jié)免疫應(yīng)答和T細胞功能平衡方面發(fā)揮重要作用。在某些免疫疾病和自身免疫性疾病中,IL2RA的異常表達可能導(dǎo)致免疫平衡的紊亂,從而引發(fā)疾病,因此被認為是免疫治療的一個重要靶點。通過調(diào)控IL2RA的功能,可以調(diào)節(jié)T細胞的活化和功能,從而在免疫治療中發(fā)揮重要的作用。

更多相關(guān)閱讀:IL2RA(CD25):CD4+CD25+Tregs亞群最特異性標(biāo)志物,抑制效應(yīng)T細胞,免疫領(lǐng)域熱點分子!

熱銷產(chǎn)品

IL2RA Recombinant Monoclonal Antibody CSB-RA011649MA1HU

驗證數(shù)據(jù)

ELISA
CSB-RA011649MA1HU ELISA

The Binding Activity of Human IL2RA with Anti-IL2RA Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA (CSB-MP011649HU3) at 2 μg/mL can bind Anti-IL2RA recombinant antibody , the EC50 is 2.463-3.353 ng/mL.

Recombinant Human Interleukin-2 receptor subunit alpha(IL2RA),partial (Active) CSB-MP011649HU3

驗證數(shù)據(jù)

SDS
CSB-MP011649HU3 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP011649HU3 ELISA1

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bind Anti-IL2RA recombinant antibody (CSB-RA011649MA1HU),the EC50 is 2.463-3.353 ng/mL.

ELISA
CSB-MP011649HU3 ELISA2

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bindHuman IL2 (CSB-MP011629HU),the EC50 is 1.693-2.039 ng/mL.

IL2RA Antibodies

IL2RA for H

IL2RA for Homo sapiens (Human)

IL2RA Proteins

IL2RA Proteins for Bos taurus (Bovine)

IL2RA Proteins for Ovis aries (Sheep)

IL2RA Proteins for Felis catus (Cat) (Felis silvestris catus)

IL2RA Proteins for Rattus norvegicus (Rat)

IL2RA Proteins for Homo sapiens (Human)

IL2RA Proteins for Mus musculus (Mouse)

IL2RA Proteins for Sus scrofa (Pig)

IL2RA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

IL2RA Proteins for Pan troglodytes (Chimpanzee)

IL2RA Proteins for Macaca mulatta (Rhesus macaque)

IL2RA ELISA Kit

IL2RA ELISA Kit for Homo sapiens (Human)

IL2RA ELISA Kit for Mus musculus (Mouse)