IL2RA
IL2RA,全名為Interleukin-2 Receptor Alpha,又稱CD25(Cluster of Differentiation 25),是一種細胞表面受體,屬于白細胞介素-2(Interleukin-2,IL-2)受體家族。是IL-2受體的α亞單位,在免疫細胞表面廣泛表達,特別是在T淋巴細胞(T細胞)中高表達。IL2RA的高表達與T細胞活化狀態(tài)密切相關(guān),是T細胞應(yīng)答的一個重要標(biāo)志。IL2RA在調(diào)節(jié)免疫應(yīng)答和T細胞功能平衡方面發(fā)揮重要作用。在某些免疫疾病和自身免疫性疾病中,IL2RA的異常表達可能導(dǎo)致免疫平衡的紊亂,從而引發(fā)疾病,因此被認為是免疫治療的一個重要靶點。通過調(diào)控IL2RA的功能,可以調(diào)節(jié)T細胞的活化和功能,從而在免疫治療中發(fā)揮重要的作用。
更多相關(guān)閱讀:IL2RA(CD25):CD4+CD25+Tregs亞群最特異性標(biāo)志物,抑制效應(yīng)T細胞,免疫領(lǐng)域熱點分子!
熱銷產(chǎn)品
● IL2RA Recombinant Monoclonal Antibody CSB-RA011649MA1HU
驗證數(shù)據(jù)
The Binding Activity of Human IL2RA with Anti-IL2RA Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA (CSB-MP011649HU3) at 2 μg/mL can bind Anti-IL2RA recombinant antibody , the EC50 is 2.463-3.353 ng/mL.
● Recombinant Human Interleukin-2 receptor subunit alpha(IL2RA),partial (Active) CSB-MP011649HU3
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bind Anti-IL2RA recombinant antibody (CSB-RA011649MA1HU),the EC50 is 2.463-3.353 ng/mL.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bindHuman IL2 (CSB-MP011629HU),the EC50 is 1.693-2.039 ng/mL.
IL2RA Antibodies
IL2RA for H
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-MA000266 | IL2RA Monoclonal Antibody | Human | ELISA,IHC |
IL2RA for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA005198 | IL2RA Antibody | Human | WB, ELISA |
CSB-PA009542 | Phospho-IL2RA (S268) Antibody | Human | WB, IHC, IF, ELISA |
CSB-PA009543 | IL2RA Antibody | Human | WB, IF, ELISA |
CSB-PA904921 | IL2RA Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA013952 | IL2RA Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA011649LA01HU | IL2RA Antibody | Human, Rat | ELISA, WB, IHC, IF |
CSB-PA011649LC01HU | IL2RA Antibody, FITC conjugated | Human | |
CSB-PA011649LD01HU | IL2RA Antibody, Biotin conjugated | Human | ELISA |
CSB-RA011649MA1HU | IL2RA Recombinant Monoclonal Antibody | Human | ELISA, IF |
IL2RA Proteins
IL2RA Proteins for Bos taurus (Bovine)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649BO1 CSB-EP011649BO1 CSB-BP011649BO1 CSB-MP011649BO1 CSB-EP011649BO1-B |
Recombinant Bovine Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649BO | Recombinant Bovine Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Ovis aries (Sheep)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649SH1 CSB-EP011649SH1 CSB-BP011649SH1 CSB-MP011649SH1 CSB-EP011649SH1-B |
Recombinant Sheep Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649SH | Recombinant Sheep Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Felis catus (Cat) (Felis silvestris catus)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649CA1 CSB-EP011649CA1 CSB-BP011649CA1 CSB-MP011649CA1 CSB-EP011649CA1-B |
Recombinant Cat Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649CA | Recombinant Cat Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Rattus norvegicus (Rat)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649RA1 CSB-EP011649RA1 CSB-BP011649RA1 CSB-MP011649RA1 CSB-EP011649RA1-B |
Recombinant Rat Interleukin-2 receptor subunit alpha (Il2ra), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649RA | Recombinant Rat Interleukin-2 receptor subunit alpha (Il2ra) | in vitro E.coli expression system |
IL2RA Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649HU1 CSB-EP011649HU1 CSB-BP011649HU1 CSB-MP011649HU1 CSB-EP011649HU1-B |
Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649HU | Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
CSB-EP011649HU2 | Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial | E.coli |
CSB-MP011649HU3 | Recombinant Human Interleukin-2 receptor subunit alpha (IL2RA), partial (Active) | Mammalian cell |
IL2RA Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649MO1 CSB-EP011649MO1 CSB-BP011649MO1 CSB-MP011649MO1 CSB-EP011649MO1-B |
Recombinant Mouse Interleukin-2 receptor subunit alpha (Il2ra), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649MO | Recombinant Mouse Interleukin-2 receptor subunit alpha (Il2ra) | in vitro E.coli expression system |
IL2RA Proteins for Sus scrofa (Pig)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649PI1 CSB-EP011649PI1 CSB-BP011649PI1 CSB-MP011649PI1 CSB-EP011649PI1-B |
Recombinant Pig Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649PI | Recombinant Pig Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011649DO1 CSB-EP011649DO1 CSB-BP011649DO1 CSB-MP011649DO1 CSB-EP011649DO1-B |
Recombinant Dog Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011649DO | Recombinant Dog Interleukin-2 receptor subunit alpha (IL2RA) | in vitro E.coli expression system |
IL2RA Proteins for Pan troglodytes (Chimpanzee)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP656443EQV CSB-EP656443EQV CSB-BP656443EQV CSB-MP656443EQV CSB-EP656443EQV-B |
Recombinant Pan troglodytes Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL2RA Proteins for Macaca mulatta (Rhesus macaque)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP689641MOW CSB-EP689641MOW CSB-BP689641MOW CSB-MP689641MOW CSB-EP689641MOW-B |
Recombinant Macaca mulatta Interleukin-2 receptor subunit alpha (IL2RA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL2RA ELISA Kit
IL2RA ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E04629h | Human soluble interleukin-2 receptor,IL-2sRα ELISA kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
IL2RA ELISA Kit for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E07440m | Mouse soluble interleukin-2 receptor,sIL-2Rα ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/ml |