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中文名稱:人幾丁質(zhì)酶3樣蛋白2(CHI3L2)酶聯(lián)免疫試劑盒
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貨號:CSB-EL005347HU
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規(guī)格:96T/48T
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價格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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別名:CH3L2_HUMAN ELISA Kit; CHI3L2 ELISA Kit; Chitinase 3 like 2 ELISA Kit; Chitinase-3-like protein 2 ELISA Kit; Chondrocyte protein 39 ELISA Kit; OTTHUMP00000014028 ELISA Kit; YKL 39 ELISA Kit; YKL-39 ELISA Kit; YKL39 ELISA Kit
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縮寫:
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Uniprot No.:
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:0.78 ng/ml-50 ng/ml
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靈敏度:0.19 ng/ml
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反應(yīng)時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Stem Cells
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測定原理:quantitative
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測定方法:Sandwich
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線性度:
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻
- Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis Hinsinger G et al,Mult Scler,2015
相關(guān)產(chǎn)品
靶點詳情
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功能:Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
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基因功能參考文獻:
- This study shown that CHI3L2 is regulated differently in healthy and late onset Alzheimer"s disease brain depending on the sex. PMID: 27653898
- Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy. PMID: 25477513
- These data suggest that hYKL-39 is a novel growth and differentiation factor involved in cartilage homeostasis. PMID: 23291184
- YKL-39 possesses a chitinase-like fold, but lacks key active-site residues required for catalysis. PMID: 22742450
- ERK1/2 phosphorylation by CHI3L2 inhibits cell mitogenesis and proliferation. PMID: 22211103
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亞細胞定位:Secreted.
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蛋白家族:Glycosyl hydrolase 18 family
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組織特異性:Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta.
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數(shù)據(jù)庫鏈接:
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