IL17A
白細胞介素- 17a是一種由IL17A基因編碼的人類蛋白質。是IL17RA和IL17RC的配體。IL17家族是一類由CD4+T細胞分泌的促炎細胞因子,包括IL17A在內共計6個成員。IL17A在染色體6p12.2,由Il17R傳遞信號,可以誘導多種炎癥因子表達,介導炎癥反應加速機體修復,以發(fā)揮保護作用。在慢性炎癥情況下,IL17A通過激活NF-?B、JAK/STAT等信號通路,持續(xù)促進細胞因子、趨化因子和基質金屬蛋白酶等的釋放及免疫細胞浸潤,促進疾病的發(fā)生發(fā)展。此外,IL17A還可以促進多種血管生成調節(jié)因子的分泌,促進腫瘤血管的形成和轉移。
熱銷產品
Recombinant Human Interleukin-17A(IL17A)(T26A) (Active) CSB-BP624104HU(M)
驗證數(shù)據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL17A at 2 μg/ml can bind Anti-IL17A recombinant antibody (CSB-RA624104MA1HU), the EC50 is 1.818-2.170 ng/mL.
IL17A Antibodies
IL17A for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA011597GA01HU | IL17A Antibody | Human | ELISA,IHC |
CSB-PA06659A0Rb | IL17A Antibody | Human | ELISA, IHC, IF |
CSB-PA06659B0Rb | IL17A Antibody, HRP conjugated | Human | ELISA |
CSB-PA06659C0Rb | IL17A Antibody, FITC conjugated | Human | |
CSB-PA06659D0Rb | IL17A Antibody, Biotin conjugated | Human | ELISA |
IL17A Proteins
IL17A Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP624104HU CSB-EP624104HU CSB-BP624104HU CSB-MP624104HU CSB-EP624104HU-B |
Recombinant Human Interleukin-17A (IL17A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001851HU | Recombinant Human Interleukin-17A protein (IL17A) | E.Coli |
CSB-AP004331HU | Recombinant Human Interleukin-17A (IL17A) (Active) | E.coli |
CSB-AP004341HU | Recombinant Human Interleukin-17A (IL17A) (Active) | Mammalian cell |
CSB-AP004701HU | Recombinant Human IL17A & IL17F Heterodimer Protein (Active) | Mammalian cell |
IL17A Proteins for Rattus norvegicus (Rat)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP717213RA CSB-BP717213RA CSB-MP717213RA CSB-EP717213RA-B |
Recombinant Rat Interleukin-17A (Il17a) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A Proteins for Mus musculus (Mouse)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP720298MO CSB-EP720298MO CSB-BP720298MO CSB-MP720298MO CSB-EP720298MO-B |
Recombinant Mouse Interleukin-17A (Il17a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP004781MO | Recombinant Mouse Interleukin-17A (Il17a), partial (Active) | Mammalian cell |
IL17A Proteins for Bos taurus (Bovine)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP724243BO CSB-EP724243BO CSB-BP724243BO CSB-MP724243BO CSB-EP724243BO-B |
Recombinant Bovine Interleukin-17A (IL17A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A Proteins for Sus scrofa (Pig)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP736792PI CSB-BP736792PI CSB-MP736792PI CSB-EP736792PI-B |
Recombinant Pig Interleukin-17A (IL17A) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A ELISA Kit
IL17A ELISA Kit for Mus musculus (Mouse)
產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E04608m | Mouse Interleukin 17,IL-17 ELISA Kit | serum, plasma, tissue homogenates | 19.5 pg/ml |
IL17A ELISA Kit for Sus scrofa (Pig)
產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E08057p | Pig interleukin 17,IL-17 ELISA Kit | serum, plasma, tissue homogenates | 10 pg/mL |
IL17A ELISA Kit for Rattus norvegicus (Rat)
產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E07451r | Rat Interleukin 17,IL-17 ELISA KIT | serum, plasma, tissue homogenates | 23.43 pg/mL |
IL17A ELISA Kit for Homo sapiens (Human)
產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E12819h | Human Interleukin 17A (IL-17A/IL-17) ELISA Kit | serum, plasma, tissue homogenates | 15.6 pg/ml |