IL17A

白細胞介素- 17a是一種由IL17A基因編碼的人類蛋白質。是IL17RA和IL17RC的配體。IL17家族是一類由CD4+T細胞分泌的促炎細胞因子，包括IL17A在內共計6個成員。IL17A在染色體6p12.2,由Il17R傳遞信號，可以誘導多種炎癥因子表達，介導炎癥反應加速機體修復，以發(fā)揮保護作用。在慢性炎癥情況下，IL17A通過激活NF-?B、JAK/STAT等信號通路，持續(xù)促進細胞因子、趨化因子和基質金屬蛋白酶等的釋放及免疫細胞浸潤，促進疾病的發(fā)生發(fā)展。此外，IL17A還可以促進多種血管生成調節(jié)因子的分泌，促進腫瘤血管的形成和轉移。

熱銷產品

Recombinant Human Interleukin-17A(IL17A)(T26A) (Active) CSB-BP624104HU(M)

驗證數(shù)據

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL17A at 2 μg/ml can bind Anti-IL17A recombinant antibody (CSB-RA624104MA1HU), the EC₅₀ is 1.818-2.170 ng/mL.

IL17A Antibody

IL17A Protein

IL17A ELISA Kit

IL17A Antibodies

IL17A for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA011597GA01HU	IL17A Antibody	Human	ELISA,IHC
CSB-PA06659A0Rb	IL17A Antibody	Human	ELISA, IHC, IF
CSB-PA06659B0Rb	IL17A Antibody, HRP conjugated	Human	ELISA
CSB-PA06659C0Rb	IL17A Antibody, FITC conjugated	Human
CSB-PA06659D0Rb	IL17A Antibody, Biotin conjugated	Human	ELISA

IL17A Proteins

IL17A Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP624104HU CSB-EP624104HU CSB-BP624104HU CSB-MP624104HU CSB-EP624104HU-B	Recombinant Human Interleukin-17A (IL17A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001851HU	Recombinant Human Interleukin-17A protein (IL17A)	E.Coli
CSB-AP004331HU	Recombinant Human Interleukin-17A (IL17A) (Active)	E.coli
CSB-AP004341HU	Recombinant Human Interleukin-17A (IL17A) (Active)	Mammalian cell
CSB-AP004701HU	Recombinant Human IL17A & IL17F Heterodimer Protein (Active)	Mammalian cell

IL17A Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP717213RA CSB-BP717213RA CSB-MP717213RA CSB-EP717213RA-B	Recombinant Rat Interleukin-17A (Il17a)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL17A Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP720298MO CSB-EP720298MO CSB-BP720298MO CSB-MP720298MO CSB-EP720298MO-B	Recombinant Mouse Interleukin-17A (Il17a)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP004781MO	Recombinant Mouse Interleukin-17A (Il17a), partial (Active)	Mammalian cell

IL17A Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP724243BO CSB-EP724243BO CSB-BP724243BO CSB-MP724243BO CSB-EP724243BO-B	Recombinant Bovine Interleukin-17A (IL17A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL17A Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP736792PI CSB-BP736792PI CSB-MP736792PI CSB-EP736792PI-B	Recombinant Pig Interleukin-17A (IL17A)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli