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  4. Human RING finger protein 207(RNF207) ELISA kit

Human RING finger protein 207(RNF207) ELISA kit

  • 中文名稱：
    人環(huán)指蛋白207(RNF207)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL019870HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：

    This Human RNF207 ELISA Kit was designed for the quantitative measurement of Human RNF207 protein in serum, plasma, tissue homogenates, cell lysates. It is a Sandwich ELISA kit, its detection range is 15.6 pg/mL-1000 pg/mL and the sensitivity is 3.9 pg/mL.

  • 別名：
    RNF207 ELISA Kit; C1orf188 ELISA Kit; RING finger protein 207 ELISA Kit
  • 縮寫：
    RNF207
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Others
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human RNF207 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %97
    Range %92-101
    1:2Average %86
    Range %81-90
    1:4Average %93
    Range %89-98
    1:8Average %90
    Range %85-94
  • 回收率：
    The recovery of human RNF207 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9590-100
    EDTA plasma (n=4)10195-108
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    10002.719 2.519 2.619 2.500
    5002.172 2.072 2.122 2.003
    2501.504 1.607 1.556 1.437
    1250.996 1.061 1.029 0.910
    62.50.653 0.623 0.638 0.519
    31.20.362 0.380 0.371 0.252
    15.60.252 0.261 0.257 0.138
    00.123 0.115 0.119
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.
  • 基因功能參考文獻(xiàn)：
    1. Data indicate that plasma E3 Ligase Rnf207 (ring finger protein 207) level in acute myocardial infarction patients increased significantly compared with that in healthy people. PMID: 25599194
    2. RNF207 is an important regulator of action potential duration, likely via effects on HERG trafficking and localization in a heat shock protein-dependent manner. PMID: 25281747
    3. Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19305408
    4. Genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19305409
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 32947

    OMIM: 616923

    KEGG: hsa:388591

    STRING: 9606.ENSP00000367173

    UniGene: Hs.716549