Human Stanniocalcin-2(STC2) ELISA kit
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中文名稱:人斯鈣素-2(STC2)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-EL022822HU
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規(guī)格:96T/48T
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價(jià)格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:
This Human STC2 ELISA Kit was designed for the quantitative measurement of Human STC2 protein in serum, plasma, tissue homogenates, cell lysates. It is a Sandwich ELISA kit, its detection range is 31.2 pg/mL-2000 pg/mL and the sensitivity is 7.8 pg/mL.
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別名:Stanniocalcin 2 ELISA Kit; Stanniocalcin related protein ELISA Kit; Stanniocalcin-2 ELISA Kit; Stanniocalcin-related protein ELISA Kit; Stanniocalcin2 ELISA Kit; STC 2 ELISA Kit; STC related protein ELISA Kit; STC-2 ELISA Kit; STC-related protein ELISA Kit; STC2 ELISA Kit; STC2_HUMAN ELISA Kit; STCRP ELISA Kit
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縮寫:
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Uniprot No.:
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma, tissue homogenates, cell lysates
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檢測(cè)范圍:31.2 pg/mL-2000 pg/mL
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靈敏度:7.8 pg/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Signal Transduction
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human STC2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 87 Range % 82-91 1:2 Average % 94 Range % 89-98 1:4 Average % 107 Range % 103-110 1:8 Average % 110 Range % 104-114 -
回收率:
The recovery of human STC2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 95 91-99 EDTA plasma (n=4) 103 98-108 -
標(biāo)準(zhǔn)曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. pg/ml OD1 OD2 Average Corrected 2000 2.096 2.103 2.100 1.982 1000 1.641 1.598 1.620 1.502 500 1.105 1.201 1.153 1.035 250 0.666 0.672 0.669 0.551 125 0.434 0.442 0.438 0.320 62.5 0.268 0.256 0.262 0.144 31.25 0.211 0.201 0.206 0.088 0 0.116 0.120 0.118 -
數(shù)據(jù)處理:
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
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基因功能參考文獻(xiàn):
- MiR-184 was confirmed to directly target STC2 in glioblastoma cells PMID: 28887636
- Results show that STC2 promotes head and neck squamous cell carcinoma cell proliferation, tumor growth, and metastasis through the PI3K/AKT/Snail pathway. PMID: 27863406
- STC2 promotes colorectal cancer tumorigenesis and epithelial-mesenchymal transition (EMT) progression through activating ERK/MEK and PI3K/AKT signaling pathways. PMID: 27662663
- Our results demonstrated the contrasting effects of STC1 and STC2-derived peptides on human macrophage foam cell formation associated with ACAT1 expression and on HASMC migration. PMID: 27346255
- Mus81 knockdown suppresses proliferation and survival of HCC cells likely by downregulating STC2 expression, implicating Mus81 as a therapeutic target for HCC. PMID: 27939696
- These findings indicated that STC2 may promote osteoblast differentiation and mineralization by regulating ERK activation PMID: 27878259
- STC2 is involved in regulating PAPP-A activity during the development of atherosclerosis PMID: 26983002
- Data suggest that stanniocalcin 1 and 2 (STC1, STC2) participate in inhibition of proteolytic activity of pregnancy-associated plasma protein-A (PAPP-A) during folliculogenesis. PMID: 26874357
- Up-regulation of CDK2 and CDK4 and down-regulation of cell cycle inhibitors p16 and p21 were observed after the delivery of STC2. Furthermore, STC2 transduction activated pAKT and pERK 1/2 signal pathways. PMID: 26424558
- This study utilized ER+ IBC to identify a metagene including ABAT and STC2 as predictive biomarkers for endocrine therapy resistance. PMID: 25771305
- STC2 may inhibit epithelial-mesenchymal transition at least partially through the PKC/Claudin-1-mediated signaling in human breast cancer cells. PMID: 25830567
- STC2 has a role in promoting cell proliferation and cisplatin resistance in cervical cancer PMID: 26361149
- The aim of this study was to evaluate the clinical value of measuring expression levels of STC2 in colorectal cancer (CRC) patients. PMID: 25234931
- Stanniocalcin 2 may contribute to tumor development and radioresistance in cervical cancer. PMID: 25674244
- These findings suggest that STC2 can be a potential lung cancer biomarker and plays a positive role in lung cancer metastasis and progression. PMID: 25463045
- Circulating STC1 and STC2 mRNA are potentially useful blood markers for LSCC PMID: 24743310
- High STC2 expression is associated with glioma. PMID: 24729417
- Interleukin-1-induced changes in the glioblastoma secretome suggest its role in tumor progression. PMID: 24503185
- STC2 overexpression correlates to poor prognosis for nasopharyngeal carcinomas. PMID: 24606961
- stanniocalcin 2 (STC2) was the most highly upregulated gene in anti-VEGF antibody-treated tumors PMID: 24375080
- Our results indicate that STC2 could be a useful molecular blood marker for predicting tumor progression by monitoring CTCs in patients with gastric cancer. PMID: 24100594
- Stanniocalcin-1 and -2 promote angiogenic sprouting in HUVECs via VEGF/VEGFR2 and angiopoietin signaling pathways. PMID: 23664860
- High STC2 expression levels are associated with disease recurrence in patients with gastric cancer. PMID: 23548070
- High STC2 expression is associated with lymph node metastasis in squamous cell/adenosquamous carcinomas and adenocarcinoma of gallbladder. PMID: 23906305
- STC2 is upregulated in hepatocellular carcinoma and promotes cell proliferation and migration. PMID: 23187001
- These findings point to three novel functions of STC2, and suggest that STC2 interacts with HO1 to form a eukaryotic 'stressosome' involved in the degradation of heme. PMID: 22503972
- High STC2 is associated with lymph node metastases in squamous cell esophageal carcinoma. PMID: 20734150
- Human stanniocalcin-1 or -2 expressed in mice reduces bone size and severely inhibits cranial intramembranous bone growth. PMID: 20174869
- High expression level of Stanniocalcin 2 is associated with gastric cancer. PMID: 20422456
- STC2 is a positive regulator in tumor progression at hypoxia. PMID: 20619259
- STC2 is a HIF-1 target gene and is involved in the regulation of cell proliferation. PMID: 19786016
- STC-2 can act as a potent growth inhibitor and reduce intramembranous and endochondral bone development and skeletal muscle growth, implying that these tissues are specific physiological targets of stanniocalcins PMID: 15367391
- Recombinant human and fish STC2 proteins were generated and found to be N-glycosylated homodimers. STC2 is a functional homodimeric glycoprotein, and thecal cell-derived STC2 could play a paracrine role during follicular development. PMID: 15486227
- NTN4, TRA1, and STC2 have roles in progression of breast cancer PMID: 17545519
- The induction of GDF15 and STC2 is likely specific to MK-4, vitamin K2 analog. PMID: 17909264
- elevated expression of STC-1 or STC-2 act as survival factors also for breast cancer cells and thereby contribute to tumor dormancy. PMID: 18355956
- STC2 was aberrantly hypermethylated in human cancer cells. PMID: 18394600
- Stanniocalcin 2 expression is regulated by hormone signalling and negatively affects breast cancer cell viability in vitro. PMID: 18492817
- stanniocalcin 2 overexpression in a prostate cancer cell line promoted prostate cancer cell growth, indicating its oncogenic property PMID: 19298603
- Increased STC2 gene expression is associated with colorectal cancer. PMID: 19415750
- Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma. PMID: 19582875
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亞細(xì)胞定位:Secreted.
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蛋白家族:Stanniocalcin family
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組織特異性:Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes.
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數(shù)據(jù)庫(kù)鏈接:
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