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Human Tetranectin(CLEC3B) ELISA kit

  • 中文名稱：
    人四連接素(CLEC3B)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL005531HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
        CLEC3B，全名C型凝集素域家族3成員B，是一種跨膜蛋白，參與細(xì)胞黏附和信號傳導(dǎo)等生物過程。它在肝病、癌癥和心血管疾病等疾病中可能扮演重要角色。近年來，CLEC3B還被發(fā)現(xiàn)對肝細(xì)胞的保護作用，具有很高的研究價值。
        華美生物所提供的Human Tetranectin(CLEC3B) ELISA kit屬于ELISA檢測試劑盒，采用雙抗夾心法定量檢測人血清、血漿、組織勻漿樣本中的CLEC3B，其靈敏度為0.39 ng/ml，檢測范圍為1.56 ng/ml- 100 ng/ml。
     
  • 別名：
    C type lectin domain family 3 member B ELISA Kit; C-type lectin domain family 3 member B ELISA Kit; Clec3b ELISA Kit; Plasminogen kringle 4 binding protein ELISA Kit; Plasminogen kringle 4-binding protein ELISA Kit; TETN_HUMAN ELISA Kit; Tetranectin (plasminogen binding protein) ELISA Kit; Tetranectin ELISA Kit; TN ELISA Kit; TNA ELISA Kit
  • 縮寫：
    CLEC3B
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    1.56 ng/ml- 100 ng/ml
  • 靈敏度：
    0.39 ng/ml
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Others
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 最新研究進展：
    CLEC3B是一種由CLEC3B基因編碼的蛋白質(zhì)，也被稱為牙齦溝液蛋白GCP-2。CLEC3B在人體免疫系統(tǒng)中發(fā)揮著重要作用，可通過識別病原體或潛在損傷信號，介導(dǎo)免疫反應(yīng)。最近的研究表明，CLEC3B還可能與其他生物學(xué)過程有關(guān)，如肝臟再生、炎癥反應(yīng)和腫瘤的生長和轉(zhuǎn)移等。此外，CLEC3B的檢測也被用于診斷某些疾病和監(jiān)測其疾病進程。
     
  • 功能：
    Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
  • 基因功能參考文獻：
    1. Low CLEC3B expression is associated with clear cell renal cell carcinoma. PMID: 30066941
    2. The present study identified the CLEC3B p.S106G as a novel longevity-associated variant, raising the novel hypothesis that tetranectin, encoded by CLEC3B, plays a role in human longevity and aging PMID: 27154906
    3. TMEM88, CCL14, and CLEC3B genes were stable and available in predicting the survival and palindromia time of hepatocellular carcinoma. These genes could function as potential prognostic genes contributing to improve patients' outcomes and survival PMID: 28718365
    4. study suggests that increased serum TN level is associated with the presence and severity of diseased coronary arteries in patients with stable CAD. PMID: 26621497
    5. results predict that a positive TN expression of both tumour tissue and serum points to a more favourable outcome for ovarian cancer patients PMID: 25846370
    6. analyze the immunohistochemical localization of tetranectin in gastric adenocarcinomas and the adjacent tissues of the wall of the stomach PMID: 11962752
    7. Tetranectin may play an important role in the survival of islets in the liver after islet transplantation. PMID: 15848710

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  • 亞細(xì)胞定位：
    Secreted.
  • 組織特異性：
    Found in plasma.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11891

    OMIM: 187520

    KEGG: hsa:7123

    STRING: 9606.ENSP00000296130

    UniGene: Hs.476092