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Human soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK)ELISA Kit

  • 中文名稱:
    人可溶性腫瘤壞死因子樣凋亡微弱誘導(dǎo)劑(sTWEAK)酶聯(lián)免疫試劑盒
  • 貨號(hào):
    CSB-E16492h
  • 規(guī)格:
    96T/48T
  • 價(jià)格:
    ¥3600/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
        TNFSF12(腫瘤壞死因子超家族成員12)是一種細(xì)胞因子蛋白,其可以結(jié)合與其受體HVEM相互作用并促進(jìn)T細(xì)胞和NK細(xì)胞的增殖和激活。TNFSF12在腫瘤治療中具有很大的潛力,可以用于提高T細(xì)胞介導(dǎo)的免疫應(yīng)答,抑制腫瘤生長(zhǎng)和擴(kuò)散。TNFSF12在人體中廣泛表達(dá),尤其在淋巴組織和免疫細(xì)胞中表達(dá)較高。
        華美生物所提供的Human soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK)ELISA Kit屬于ELISA檢測(cè)試劑盒,采用雙抗夾心法定量檢測(cè)人血清、血漿、組織勻漿樣本中的TNFSF12,其靈敏度為0.078 ng/ml,檢測(cè)范圍為0.312 ng/ml-20 ng/ml。
     
  • 別名:
    APO 3 ligand ELISA Kit; APO 3L ELISA Kit; APO3 ligand ELISA Kit; APO3/DR3 ligand ELISA Kit; APO3L ELISA Kit; DR3LG ELISA Kit; MGC129581 ELISA Kit; MGC20669 ELISA Kit; secreted form ELISA Kit; TNF-related weak inducer of apoptosis ELISA Kit; TNF12_HUMAN ELISA Kit; TNFSF 12 ELISA Kit; Tnfsf12 ELISA Kit; TNFSF12 protein ELISA Kit; Tumor necrosis factor (ligand) superfamily member 12 ELISA Kit; Tumor necrosis factor ligand superfamily member 12 ELISA Kit; Tumor necrosis factor superfamily member 12 ELISA Kit; TWEAK ELISA Kit; UNQ181/PRO207 ELISA Kit
  • 縮寫:
    TNFSF12
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍:
    0.312 ng/ml-20 ng/ml
  • 靈敏度:
    0.078 ng/ml
  • 反應(yīng)時(shí)間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測(cè)波長(zhǎng):
    450 nm
  • 研究領(lǐng)域:
    Cardiovascular
  • 測(cè)定原理:
    quantitative
  • 測(cè)定方法:
    Sandwich
  • 精密度:
     
  • 線性度:
     
  • 回收率:
     
  • 標(biāo)準(zhǔn)曲線:
     
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 最新研究進(jìn)展:
    TNFSF12是一種細(xì)胞因子,也被稱為TWEAK。最新的研究表明,它在肝癌等多種腫瘤的發(fā)生和進(jìn)展中發(fā)揮著關(guān)鍵作用,并且可能成為治療這些腫瘤的新靶點(diǎn)之一。
  • 功能:
    Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
  • 基因功能參考文獻(xiàn):
    1. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    2. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
  • 亞細(xì)胞定位:
    Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.
  • 蛋白家族:
    Tumor necrosis factor family
  • 組織特異性:
    Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 11927

    OMIM: 602695

    KEGG: hsa:407977

    UniGene: Hs.54673