-
中文名稱:小鼠嗜酸粒細胞趨化蛋白Eotaxin 2(Eotaxin 2/CCL24)酶聯(lián)免疫試劑盒
-
貨號:CSB-E07278m
-
規(guī)格:96T/48T
-
價格:¥3200/¥2500
-
其他:
產(chǎn)品詳情
-
產(chǎn)品描述:
This Mouse CCL24 ELISA Kit was designed for the quantitative measurement of Mouse CCL24 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 15.6 pg/ml - 1000 pg/ml and the sensitivity is 3.9 pg/ml.
-
別名:Ccl24 ELISA Kit; Scya24 ELISA Kit; C-C motif chemokine 24 ELISA Kit; Eosinophil chemotactic protein 2 ELISA Kit; Eotaxin-2 ELISA Kit; Small-inducible cytokine A24 ELISA Kit
-
縮寫:
-
Uniprot No.:
-
種屬:Mus musculus (Mouse)
-
樣本類型:serum, plasma, tissue homogenates
-
檢測范圍:15.6 pg/ml - 1000 pg/ml
-
靈敏度:3.9 pg/ml
-
反應(yīng)時間:1-5h
-
樣本體積:50-100ul
-
檢測波長:450 nm
-
研究領(lǐng)域:Immunology
-
測定原理:quantitative
-
測定方法:Sandwich
-
數(shù)據(jù)處理:
-
貨期:3-5 working days
引用文獻
- Protein tyrosine phosphatase 11 acts through RhoA/ROCK to regulate eosinophil accumulation in the allergic airway Xu C, et al,Faseb Journal,2019
相關(guān)產(chǎn)品
靶點詳情
-
功能:Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
-
基因功能參考文獻:
- the increased airway eosinophils and mucous cell metaplasia in house dust mite-challenged Cd163-/- mice are mediated by augmented CCL24 production PMID: 26376364
- this study shows that TPL-2 inhibits Ccl24 expression in lung dendritic cells, and blockade of Ccl24 prevents the exaggerated airway eosinophilia and lung inflammation in mice given house dust mites-pulsed Map3k8-/- dendritic cells PMID: 27484038
- production in M-CSF-induced bone marrow-derived macrophages is synergistically induced by IL-4 and IL-10 PMID: 25267883
- Autologous transfer of peritoneal macrophages in to the airways of asthmatic mice reduces eotaxin production. PMID: 24077949
- Data indicate that eotaxin 2 (CCL-24), which is known to influence eosinophil migration, was highly up-regulated in broncho-alveolar macrophages (BAMs). PMID: 23685352
- The oesophageal production of CCL24 upon IL-13 stimulation is sufficient to promote eosinophil migration. PMID: 20030665
- Results demonstrate a cooperative mechanism between interleukin-13 and eotaxin-2, where IL-13 mediates allergen-induced eotaxin-2 expression, and eotaxin-2 mediates IL-13-induced airway eosinophilia. PMID: 15647285
- Distinct acidic and basic residues within CCR3 determine both receptor expression and activation by the eotaxins. PMID: 16102831
- The eotaxin-2 pathway plays a fundamental role in eosinophil recruitment during ovalbumin-induced experimental asthma. PMID: 16210640
- eosinophils via chemokine (C-C) receptor 3 have a central role in chronic allergic airway disease PMID: 17060636
- CCL24 seems important for recruitment of eosinophils into BAL. PMID: 18850374
顯示更多
收起更多
-
亞細胞定位:Secreted.
-
蛋白家族:Intercrine beta (chemokine CC) family
-
組織特異性:Highest expression in jejunum and spleen. Lower levels found in liver and lung. No expression detected in kidney, thymus, brain or testis.
-
數(shù)據(jù)庫鏈接:
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-