Rat Interleukin 1β,IL-1β ELISA Kit
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中文名稱:大鼠白介素1β (IL-1β)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E08055r
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規(guī)格:96T/48T
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價(jià)格:¥3200/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:IL1B (白細(xì)胞介素-1β,Interleukin-1β) 是由許多不同類型的細(xì)胞產(chǎn)生的促炎癥細(xì)胞因子,包括單核細(xì)胞、巨噬細(xì)胞、樹突狀細(xì)胞、T細(xì)胞和B細(xì)胞等。IL1B 參與了許多生理和病理過程,包括炎癥、感染、腫瘤、自身免疫疾病等。華美生物所提供的Rat Interleukin 1β,IL-1β ELISA Kit屬于ELISA檢測(cè)試劑盒,采用雙抗夾心法定量檢測(cè)大鼠血清、血漿、組織勻漿樣本中的IL1B,其靈敏度為0.039 ng/ml,檢測(cè)范圍為0.156 ng/ml-10 ng/ml。
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別名:Il1bInterleukin-1 beta ELISA kit; IL-1 beta ELISA kit
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縮寫:
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Uniprot No.:
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種屬:Rattus norvegicus (Rat)
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樣本類型:serum, plasma, tissue homogenates.
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檢測(cè)范圍:0.156 ng/ml-10 ng/ml.
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靈敏度:0.039 ng/ml.
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Immunology
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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標(biāo)準(zhǔn)曲線:
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
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- Boswellic acids ameliorate neurodegeneration induced by AlCl3: the implication of Wnt/β-catenin pathway EA Mohamed,Environmental science and pollution research international,2022
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- Telfairia occidentalis mitigates dextran sodium sulfate‐induced ulcerative colitis in rats via suppression of oxidative stress, lipid peroxidation, and inflammation JO Oladele,Journal of food biochemistry,2021
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- Rosiglitazone ameliorated airway inflammation induced by cigarette smoke via inhibiting the M1 macrophage polarization by activating PPARγ and RXRα H Feng,International Immunopharmacology,2021
- Postconditioning attenuates myocardial ischemia?reperfusion injury by inhibiting complement activation and upregulation of miR?499 Z Huang,Experimental and Therapeutic Medicine,2021
- Evaluation of the Ameliorative Effect of Zinc Nanoparticles against Silver Nanoparticle–Induced Toxicity in Liver and Kidney of Rats AM Shehata,Biological Trace Element Research,2021
- Nephroprotective effect of Vanillic acid in STZ-induced diabetic rats S Kumari,Journal of Diabetes & Metabolic Disorders,2021
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- Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides Y Tian,Journal of Ethnopharmacology,2021
- miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein PY Nie,Journal of Neuroinflammation,2021
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- Astragaloside IV Protects Against Diabetic Nephropathy by Inhibiting Pyroptosis Based on NOX4/TXNIP/NLRP3 Pathway Y Zhang,Authorea,2020
- Acetazolamide ameliorates the severity of collagen-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting Wnt/β-catenin pathway Y Mu,International immunopharmacology,2020
- Effects of Intra-Articular D-Amino Acids Combined With Systemic Vancomycin on an Experimental Staphylococcus Aureus-Induced Periprosthetic Joint Infection Y Li,Research Square,2020
- Oxidative stress-mediated induction of pulmonary oncogenes, inflammatory, and apoptotic markers following time-course exposure to ethylene glycol monomethyl ether in rats Oluwatobi T. Somade,Metabolism Open,2020
- G protein-coupled receptor 30 activation protects hepatic ischemia-reperfusion injury of liver tissue through inhibiting NLRP3 in the rat model Y Qin,Journal of histotechnology,2020
- Ginkgo biloba Extract Attenuates Methotrexate-Induced Testicular Injury in Rats: Cross-talk Between Oxidative Stress, Inflammation, Apoptosis, and miRNA-29a Expression IO Sherif,Integrative cancer therapies,2020
- Ketone Metabolite β-Hydroxybutyrate Ameliorates Inflammation After Spinal Cord Injury by Inhibiting the NLRP3 Inflammasome G Kong,Neurochemical research,2020
- Integration Traditional Chinese Medicine and Nibble Debridement and Dressing Method Reduce Thrombosis and Inammatory J Li,Research Square,2020
- Extract of andrographis paniculata for cognitive enhancement MSH SUMON,Trea,2020
- Sesame oil mitigates memory impairment, oxidative stress, and neurodegeneration in a rat model of Alzheimer's disease. A pivotal role of NF-κB/p38MAPK/BDNF/PPAR-γ pathways EA Mohamed,Journal of Ethnopharmacology,2020
- Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis S Zhang,Frontiers in Pharmacology,2020
- Pirfenidone attenuates gentamicin-induced acute kidney injury by inhibiting inflammasome-dependent NLRP3 pathway in rats MH Sharawy,Life Sciences,2020
- Methanol Extract of Chasmanthera dependens Stem Mitigates against Mechanisms Involved in Piroxicam-induced Liver Damage in Rat TS Abiola,Journal of Complementary and Alternative Medical Research,2020
- Effect of Qinbai Qingfei Concentrated Pellets on substance P and neutral endopeptidase of rats with post-infectious cough W Jia,BMC Complementary Medicine and Therapies,2020
- Hepatic oxidative stress, up-regulation of pro-inflammatory cytokines, apoptotic and oncogenic markers following 2-methoxyethanol administrations in rats OT Somade,Biochemistry and Biophysics Reports,2020
- Ethylene glycol monomethyl ether-induced testicular oxidative stress and time-dependent up-regulation of apoptotic, pro-inflammatory, and oncogenic markers in rats OT Somade,Metabolism Open,2020
- Zhen-Wu-Tang Protects IgA Nephropathy in Rats by Regulating Exosomes to Inhibit NF-κB/NLRP3 Pathway H Li,Frontiers in Pharmacology,2020
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相關(guān)產(chǎn)品
問答及客戶評(píng)論
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Tested application: ELISA
Test sample: Tissue homogenate (brain)
Species: Rat
Review: The test is carried out in a simple way, the samples in repetitions come out very repetitive, only small differences in groups. The samples were not diluted, the results approximated to half the standard curve. The samples were converted to the amount of protein calculated using the BCA method.
靶點(diǎn)詳情
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最新研究進(jìn)展:IL-1β是一種由單核細(xì)胞和巨噬細(xì)胞產(chǎn)生的細(xì)胞因子,能夠介導(dǎo)炎癥和免疫反應(yīng)。最新研究發(fā)現(xiàn),IL-1β參與多種疾病的發(fā)生和發(fā)展,包括腫瘤、自身免疫病和神經(jīng)退行性疾病等。目前已有研究在探索針對(duì)IL-1β的治療方案,如使用IL-1β抑制劑等。此外,一些研究還發(fā)現(xiàn)IL-1β的多態(tài)性可能與特定疾病的風(fēng)險(xiǎn)相關(guān)。
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功能:Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
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亞細(xì)胞定位:Cytoplasm, cytosol. Lysosome. Secreted, extracellular exosome. Secreted.
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蛋白家族:IL-1 family
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數(shù)據(jù)庫(kù)鏈接:
STRING: 10116.ENSRNOP00000006308
UniGene: Rn.9869
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