Rat luteinizing hormone (LH) Elisa kit
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中文名稱:大鼠黃體生成素(LH)酶聯(lián)免疫試劑盒
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貨號:CSB-E12654r
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規(guī)格:96T/48T
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價格:¥3600/¥2500
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其他:
產品詳情
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產品描述:LH(黃體生成素)是垂體前葉的一種促性腺激素,作用于卵巢和睪丸,促進卵泡生長、排卵和黃體形成,調節(jié)雄性激素的合成和分泌。華美生物所提供的Rat luteinizing hormone (LH) Elisa kit屬于ELISA檢測試劑盒,采用競爭法定量檢測大鼠血清、血漿樣本中的LH,其靈敏度為0.15 mLU/mL,檢測范圍為0.3 mLU/mL-60 mLU/mL。
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別名:LhbLutropin subunit beta ELISA Kit; Lutropin beta chain ELISA Kit; Luteinizing hormone subunit beta ELISA Kit; LH-B ELISA Kit; LSH-B ELISA Kit; LSH-beta ELISA Kit
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縮寫:LH
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Uniprot No.:
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種屬:Rattus norvegicus (Rat)
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樣本類型:serum, plasma
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檢測范圍:0.3 mlU/ml-60 mlU/ml
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靈敏度:0.15 mlU/ml
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Signal Transduction
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測定原理:quantitative
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測定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<15% Three samples of known concentration were tested in twenty assays to assess. -
線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of rat LH in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 93 Range % 88-100 1:2 Average % 95 Range % 91-101 1:4 Average % 94 Range % 85-105 1:8 Average % 96 Range % 90-102 -
回收率:
The recovery of rat LH spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 98 93-107 EDTA plasma (n=4) 96 91-103 -
標準曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. mIU/ml OD1 OD2 Average 60 0.150 0.153 0.152 15 0.352 0.338 0.345 4.8 0.513 0.549 0.531 1.2 0.985 1.002 0.994 0.3 1.476 1.441 1.459 0 2.679 2.654 2.667 -
數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻
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- Mechanistic insight into the protective effects of fisetin against arsenic-induced reproductive toxicity in male rats MU Ijaz,Scientific reports,2023
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- Novel insights into the synergistic effects of selenium nanoparticles and metformin treatment of letrozole - induced polycystic ovarian syndrome: targeting PI3K/Akt signalling pathway, redox status and mitochondrial dysfunction in ovarian tissue HM Rabah,Redox report,2023
- Melatonin Mitigates Cisplatin-Induced Ovarian Dysfunction via Altering Steroidogenesis, Inflammation, Apoptosis, Oxidative Stress, and PTEN/PI3K/Akt/mTOR/AMPK Signaling Pathway in Female Rats A Al-Shahat,Pharmaceutics,2022
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- Protective Effect of Portulaca oleracea on Streptozotocin-Induced Type I Diabetes-Associated Reproductive System Dysfunction and Inflammation H Rakhshandeh,Molecules,2022
- Reprotoxicological Ameliorating Effect of Camel Milk against Aflatoxicosis in Male Rats BJ Mohammad,Journal of Pharmaceutical Negative Results,2022
- The Impact of Chrysin on The Folliculogenesis and Ovarian Apoptosis in Ischemia-Reperfusion Injury in The Rat Model Z Mohammadi,International Journal of Fertility and Sterility,2022
- The effects of fenugreek (trigonella foenum-graecum), sesame (sesamum indicum) and domperidone on weights and some hormones of lactating white female ra IH Ali,HIV Nursing,2022
- Prevention of Testicular Damage by Indole Derivative MMINA via Upregulated StAR and CatSper Channels with Coincident Suppression of Oxidative Stress and Inflammation: In Silico and In Vivo Validation T Afsar,Antioxidants,2022
- Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome in Wistar rats RM Salama,Food and chemical toxicology,2022
- l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity NF Khedr,Life sciences,2021
- Quercetin Inhibits ROS-p53-Bax-caspase-3 Axis of Apoptosis and Augments Gonadotropin and Testicular Hormones in Chronic Unpredictable Stress-Induced Testis Injury I Bin-Jaliah,Int. J. Morphol,2021
- Effect of Omega-3 or Omega-6 Dietary Supplementation on Testicular Steroidogenesis, Adipokine Network, Cytokines, and Oxidative Stress in Adult Male Rats A Moustafa,Oxidative Medicine and Cellular Longevity,2021
- Thymol alleviates imidacloprid-induced testicular toxicity by modulating oxidative stress and expression of steroidogenesis and apoptosis-related genes in adult male rats TM Saber,Ecotoxicology and Environmental Safety,2021
- Umbelliferone ameliorates oxidative stress and testicular injury, improves steroidogenesis and upregulates peroxisome proliferator-activated receptor gamma in type 2 diabetic rats MAM Allam,Journal of Pharmacy and Pharmacology,2021
- Quercetin Inhibits ROS-p53-Bax-caspase-3 Axis of Apoptosis and Augments Gonadotropin and Testicular Hormones in Chronic Unpredictable Stress-Induced Testis Injury I Bin-Jaliah,Int. J. Morphol,2021
- Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling MF Alotaibi,Drug Des Devel Ther,2020
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- Impact of Sleep Deprivation on the Hypothalamic-Pituitary-Gonadal Axis and Erectile Tissue Lee DS, et al,Journal of Sexual Medicine,2019
- Protective role of Ficus deltoidea against BPA-induced impairments of the follicular development, estrous cycle, gonadotropin and sex steroid hormones level of prepubertal rats Zaid SSM, et al,Journal of ovarian research,2018
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- Crataegus aronia enhances sperm parameters and preserves testicular architecture in both control and non-alcoholic fatty liver disease-induced rats Dallak M, et al,Pharmaceutical Biology,2018
- Amelioration of diabetes-\induced testicular and sperm damage in rats by cerium oxide nanoparticle treatment Tayebe Artimani.et al,ANDROLOGIA,2018
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相關產品
靶點詳情
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最新研究進展:促黃體生成素是由垂體前葉分泌的蛋白質激素,對于女性生殖周期中的排卵和黃體生成起重要作用。最新的研究發(fā)現(xiàn),LH還與男性生殖健康密切相關,可促進精子發(fā)生和成熟,并在精液中發(fā)揮重要作用。
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功能:Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
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基因功能參考文獻:
- Orchestrated Egr1 and Pitx1 activities depending on specific central and peripheral regulatory inputs could be responsible for physiologically variable Lhb gene promoter activation in vivo. PMID: 25258388
- GnRH stimulates AMPK, and AMPK inhibition suppresses GnRH-stimulated LHbeta transcription. PMID: 23518923
- data suggest that the molecular decision for LHbeta subunit to enter the regulated secretory pathway is a pre-Golgi event controlled by the C-terminal heptapeptide. PMID: 23734233
- increased LH concentration induces production of incomplete LHR transcripts in hippocampal cells and decreases immature LHR at the protein level PMID: 23678542
- Data suggest that LH beta subunit expression (and FSH beta subunit expression) is regulated by DUSP1 expression (specifically in response to high-frequency GnRH pulses); this effect may occur in association with MAPK3/1 phosphorylation. PMID: 21228211
- Complex interactions between Ahr and Esr alter Prl and luteinizing hormone (LH) synthesis by direct actions in lactotropes and gonadotropes. PMID: 21187122
- LHbeta promoter activity is further regulated by the orphan nuclear receptors, chicken ovalbumin upstream promoter-transcription factors (COUP-TFI and COUP-TFII). PMID: 20797425
- data suggest that LHbeta G1502A polymorphism may be involved in the predisposition to infertility and minimal/mild endometriosis-associated infertility, although endometriosis might be only a coincidental finding along with infertility. PMID: 20430510
- PACAP may be released from the anterior pituitary cells in a concentration which would be able to influence LH release not only in vitro but under in vivo conditions as well. PMID: 12409218
- These results suggest that GnRH directly regulates LH secretion as well as LHbeta-subunit synthesis, and that LH2 cells are a useful model for the study of LH secretion induced by several secretagogues. PMID: 12940464
- androgens acting directly on the pituitary increase FSH-beta and decrease LH-beta transcription PMID: 14512439
- identify a second functional Pitx1 region spanning positions -73 to -52 in the LHbeta gene promoter PMID: 16087728
- JNK regulates both LHbeta and FSHbeta transcription in a differential manner. PMID: 17932215
- LHbeta, FSHbeta and the common alpha-subunit mRNA's were detected in intact follicles, theca cells, corpora lutea and in meiotically competent and incompetent oocytes. PMID: 18248883
- the carboxyl-terminal sequence in the lutropin beta subunit contributes to the sorting of lutropin to the regulated pathway PMID: 18292086
- In the 14-day-old rat pituitary, the majority of GHRH target cells are cells expressing LH beta mRNA alone or in combination with GH and/or POMC mRNA. PMID: 18363807
- Results demonstrate that degradation via the proteasome is vital to GnRH-stimulated LHbeta expression, and this occurs in part by allowing proper transcription factor associations with the LHbeta promoter. PMID: 19095772
- Lhb gene transcription in rat pituitary requires GnRH-induced early growth response 1 gene expression, which is mediated by MAPK8/9 and MAPK1/3. PMID: 19710510
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亞細胞定位:Secreted.
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蛋白家族:Glycoprotein hormones subunit beta family
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