ACY1 Antibody
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中文名稱:ACY1兔多克隆抗體
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貨號:CSB-PA616041
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規(guī)格:¥1100
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圖片:
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA616041(ACY1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA616041(ACY1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse kidney tissue, human normal kidney tissue, K562 cells, Primary antibody: CSB-PA616041(ACY1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:ACY1
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別名:ACY 1 antibody; ACY-1 antibody; Acy1 antibody; ACY1_HUMAN antibody; ACY1D antibody; ACYLASE antibody; Acylase I antibody; Aminoacylase 1 antibody; Aminoacylase-1 antibody; EC 3.5.1.14 antibody; epididymis secretory protein Li 5 antibody; HEL-S-5 antibody; N acyl L amino acid amidohydrolase antibody; N-acyl-L-amino-acid amidohydrolase antibody; OTTHUMP00000212459 antibody; OTTHUMP00000212462 antibody; OTTHUMP00000212463 antibody; OTTHUMP00000212464 antibody; OTTHUMP00000212465 antibody
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宿主:Rabbit
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反應種屬:Human,Mouse
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免疫原:Fusion protein of Human ACY1
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應用范圍:ELISA,WB,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:200-1:1000 IHC 1:25-1:100 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關產(chǎn)品
靶點詳情
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功能:Catalyzes the hydrolysis of N-acetylated amino acids to acetate and free amino acids.
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基因功能參考文獻:
- with the elevated level in the disease progression of Chronic hepatitis B (CHB), ACY1 autoantibody may be a valuable serum biomarker for discriminating HBVrelated liver cirrhosis from CHB. PMID: 27633755
- Biochemical analysis showed absence of ACY1 enzyme activity in the patient's fibroblasts. PMID: 24117009
- ACY1 acts as a tumor suppressor in hepatocellular carcinoma. PMID: 24846301
- Report serum aminoacylase-1 as a novel biomarker with potential prognostic utility for long-term outcome in renal transplant recipients with delayed graft function. PMID: 23739232
- Case Report: ACY1-deficient patient presenting with autistic features. PMID: 20480396
- We concluded that ACY1 expression in colorectal cancer varies with stage and appears to play a role in cell proliferation and apoptosis PMID: 23317546
- These data suggest that aminoacylase expression is dysregulated in neuroblastoma. PMID: 21128244
- aminoacylase 1 proteins with the mutations p.Arg378Trp, p.Arg378Gln and p.Arg393His were also detected in Western blot analysis PMID: 21414403
- by complementing different active site mutants of human aminoacylase-1, study shows that catalysis occurs at the dimer interface PMID: 12933810
- first report of a patient with aminoacylase I deficiency PMID: 16274666
- Genetic deficiency of ACY1 leads to functional ACY1 deficiency and excretion of N-acetylated amino acids. PMID: 16465618
- Because hK1 amidase activity is significantly lower in urine of systolic HF patients, it can be supposed that activity of renal kallikrein-kinin system may be suppressed in this systolic heart failure. PMID: 17045186
- T347S variant of human Acy1 exhibited markedly increased catalytic efficiency against N-benzoylamino acids PMID: 18341290
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相關疾病:Aminoacylase-1 deficiency (ACY1D)
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亞細胞定位:Cytoplasm.
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蛋白家族:Peptidase M20A family
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組織特異性:Expression is highest in kidney, strong in brain and weaker in placenta and spleen.
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數(shù)據(jù)庫鏈接:
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