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AP1G1 Antibody

  • 中文名稱(chēng)：
    AP1G1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA001861LA01HU
  • 規(guī)格：
    ￥440
  • 促銷(xiāo)：
    小規(guī)格抗體限時(shí)一口價(jià)
  • 圖片：
    • Western Blot
      Positive WB detected in:K562 whole cell lysate,Mouse kidney tissue
      All lanes:AP1G1 antibody at 3.4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 92 KDa
      Observed band size: 92 KDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA001861LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA001861LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA001861LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) AP1G1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AP1G1
  • 別名：
    Adapter-related protein complex 1 subunit gamma-1 antibody; Adaptor protein complex AP 1 gamma 1 subunit antibody; Adaptor protein complex AP 1 subunit gamma 1 antibody; Adaptor protein complex AP-1 subunit gamma-1 antibody; Adaptor related protein complex 1 gamma 1 subunit antibody; ADTG antibody; AP 1 complex subunit gamma 1 antibody; AP-1 complex subunit gamma-1 antibody; AP1G1 antibody; AP1G1_HUMAN antibody; CLAPG1 antibody; Clathrin assembly protein complex 1 gamma 1 large chain antibody; Clathrin assembly protein complex 1 gamma large chain antibody; Clathrin assembly protein complex 1 gamma-1 large chain antibody; Clathrin associated/assembly/adaptor protein large gamma 1 antibody; Gamma1 adaptin antibody; Gamma1-adaptin antibody; Golgi adaptor HA1/AP1 adaptin gamma subunit antibody; Golgi adaptor HA1/AP1 adaptin subunit gamma 1 antibody; Golgi adaptor HA1/AP1 adaptin subunit gamma-1 antibody; MGC18255 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human AP-1 complex subunit gamma-1 protein (592-686AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，AP1G1 Antibody (CSB-PA001861LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于A(yíng)P1G1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA001861LB01HU AP1G1 Antibody, HRP conjugated ELISA
    FITC CSB-PA001861LC01HU AP1G1 Antibody, FITC conjugated
    Biotin CSB-PA001861LD01HU AP1G1 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes.
  • 基因功能參考文獻(xiàn)：
    1. Data indicate a functional link between adaptor protein complex 1 (AP-1) and the WD repeat protein 11 (WDR11) complex. PMID: 29426865
    2. High ASCT2 expression is associated with drug resistance head and neck squamous cell carcinoma. PMID: 28823958
    3. Depletion of the gamma2 or mu1A (AP1M1) subunits of AP-1, but not of gamma1 (AP1G1), precludes Nef-mediated lysosomal degradation of CD4. PMID: 27909244
    4. Interaction between Rab4b and AP1gamma allows the budding of clathrin-coated vesicles for subsequent traffic to recycling endosomes. PMID: 24006255
    5. Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.The interaction may play a role in membrane trafficking between the trans-Golgi network and endosomes. PMID: 11872161
    6. crystal structure of the human gamma 1-adaptin ear domain consists solely of an immunoglobulin-like fold, unlike the alpha-adaptin ear domain PMID: 12042876
    7. Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation PMID: 16867982

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  • 亞細(xì)胞定位：
    Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle.
  • 蛋白家族：
    Adaptor complexes large subunit family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 555

    OMIM: 603533

    KEGG: hsa:164

    STRING: 9606.ENSP00000377148

    UniGene: Hs.461253