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ATE1 Antibody

  • 中文名稱：
    ATE1兔多克隆抗體
  • 貨號：
    CSB-PA002268LA01HU
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時一口價
  • 圖片：
    • IHC image of CSB-PA002268LA01HU diluted at 1:200 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA002268LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ATE1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    AI225793 antibody; Arginine tRNA protein transferase 1 antibody; Arginine-tRNA--protein transferase 1 antibody; Arginyl-tRNA--protein transferase 1 antibody; Arginyl-tRNA-protein transferase antibody; Arginyltransferase 1 antibody; Ate1 antibody; ATE1_HUMAN antibody; AW547406 antibody; EC 2.3.2.8 antibody; MGC26724 antibody; OTTHUMP00000020637 antibody; OTTHUMP00000058665 antibody; R transferase 1 antibody; R-transferase 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Arginyl-tRNA--protein transferase 1 protein (105-253AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，ATE1 Antibody (CSB-PA002268LA01HU)，的標(biāo)記方式是Non-conjugated。對于ATE1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA002268LB01HU ATE1 Antibody, HRP conjugated ELISA
    FITC CSB-PA002268LC01HU ATE1 Antibody, FITC conjugated
    Biotin CSB-PA002268LD01HU ATE1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues.
  • 基因功能參考文獻(xiàn)：
    1. Ate1 is downregulated in several types of human cancer samples at the protein level, and that its transcription level inversely correlates with metastatic progression and patient survival. PMID: 26686093
    2. Data indicate that arginyltransferase 1 (ATE1) function controls Myocardin-related transcription factor A (MRTF-A) activity. PMID: 25381249
  • 亞細(xì)胞定位：
    [Isoform ATE1-1]: Nucleus. Cytoplasm.; [Isoform ATE1-2]: Cytoplasm.
  • 蛋白家族：
    R-transferase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 782

    OMIM: 607103

    KEGG: hsa:11101

    STRING: 9606.ENSP00000224652

    UniGene: Hs.632080