Avpr1a Antibody
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中文名稱:Avpr1a兔多克隆抗體
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貨號(hào):CSB-PA15624A0Rb
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規(guī)格:¥440
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促銷:
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Rattus norvegicus (Rat) Avpr1a Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:Avpr1aVasopressin V1a receptor antibody; V1aR antibody; AVPR V1a antibody; Antidiuretic hormone receptor 1a antibody; Vascular/hepatic-type arginine vasopressin receptor antibody
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宿主:Rabbit
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反應(yīng)種屬:Rat, Mouse
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免疫原:Recombinant Rat Vasopressin V1a receptor protein (7-52AA)
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免疫原種屬:Rattus norvegicus (Rat)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,Avpr1a Antibody (CSB-PA15624A0Rb),的標(biāo)記方式是Non-conjugated。對(duì)于Avpr1a Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB, IHC
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推薦稀釋比:
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation.
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基因功能參考文獻(xiàn):
- data support a role for altered signalling via central Avpr1a in PreNatal Stress-induced sex-dependent changes in social memory. PMID: 26613552
- Increased expression of V1aR in hypothalamic paraventricular nucleus influences autonomic cardiovascular regulation and demarcates vulnerability to stress. PMID: 27810519
- Vasopression V1a receptor binding density was higher in juveniles than in adults in regions associated with reward and socio-spatial memory and higher in adults than in juveniles in key regions of the social decision-making network and in cortical regions. PMID: 27389643
- Vasopressin V1A receptors mediate the beneficial effects of hypercapnia on microcirculatory oxygenation during sepsis. PMID: 26969105
- Stimulation of V1a receptor induces the downregulation of GLUT9, reabsorption urate transporter, together with the upregulation of ABCG2 and NPT1, secretion urate transporters, all changes of which clearly lead to increase in renal uric acid clearance. PMID: 26935049
- This study demonstrated that Vasopressin V1a receptor within the PVN of lactating rats mediate maternal care and anxiety-related behaviour. PMID: 26909846
- The combination of V1aR and V2R antagonists prevented cardiac/renal damage in rat model of hypertensive heart failure. PMID: 26248278
- AVP plays an important role in modulating the salt-induced sympathoexcitation and high blood pressure, via V1a receptors, within the paraventricular nucleus of male rats. PMID: 26354848
- Myocardial infarction and chronic stress cause significant but differential changes in the regulation of V1a receptors expression in the brain and the kidney. PMID: 25169016
- Oxytocin inhibits ASICs through V1A receptors in sensory neurons modulating nociception and pain. PMID: 24641084
- Mice lacking V1a receptors have less secondary brain damage following experimental traumatic brain injury. PMID: 23441636
- These data suggest that in SHR rats, activation of plasma AVP and the renal V(1A) receptor occurs during developing hypertension, with downregulation when hypertension is established. PMID: 23246465
- vasopressin V(1a) receptors exert a modulatory influence on the neural response to a predator odor PMID: 23219972
- High extracellular glucose downregulates vasopressin V1A receptors on rat mesangial cells and modulates their signal transduction properties via protein kinase (PK)C activation. PMID: 22352691
- The data showed that activation of arginine vasopressin V1a receptors by arginine vasopressin in the lateral septum is important for social recognition in both sexes, and that the roles of septal V1a receptors in social recognition change during aging. PMID: 22033278
- V1a vasopressin receptor mRNA and protein expressions are significantly down-regulated in cerebellum from post-infarct heart failure; they are not affected by mild chronic stressing. PMID: 21652017
- The results of this study suggested that, in humans, vasopressin, acting on V1AR, produces inhibition of capsaicin-induced pain by activating endogenous (stress induced) analgesic systems. PMID: 22019732
- V(A)R plays a physiological role in preventing urine leakage. PMID: 21228111
- Aldosterone requires vasopressin V1a receptors on intercalated cells to mediate acid-base homeostasis. PMID: 21415155
- Spinal V1a receptors are not required for elevations of mean arterial pressure under conditions of acute or chronic osmotic stress in conscious rats. PMID: 21123759
- V(1a) receptor plays an important role in argipressin-mediated regulation of vascular reactivity and calcium sensitivity following hemorrhagic shock. PMID: 19577256
- central V(1)Rs are involved in potentiation of cardiovascular responses to acute stress in chronically stressed rats, infarcted rats, and chronically stressed infarcted rats PMID: 20042688
- mRNA expression for V(1a) and V(1b) AVP receptors in isolated rat adrenal chromaffin cells treated with vasopressin PMID: 12047911
- Activation of V1A vasopressin receptor induces a rise of both cytoplasmic and nuclear calcium in cultured cortical astrocytes. PMID: 12088846
- compared expression of V1a, V1b and V2 vasopressin receptor mRNA in the renal cortex, renal medulla and the heart of hypertensive renin transgenic TGR(mRen2)27 rats (TGR) and of their parent normotensive Sprague Dawley (SD) strain PMID: 12369733
- the presence of vasopressin V1a receptors on gonadotropes supports the controversial hypothesis of a local direct action of the neuropeptide on this cell type PMID: 12399435
- Increased amounts of renal cortex V1A receptors in spontaneously hypertensive rats play an important role in the pathophysiology of hypertension. PMID: 12566855
- Vasopressin binding sites of the V1a receptor type are present in all laminae of the central gray at all segmental levels, whereas oxytocin binding sites are found only in the superficial layers of the dorsal horn. PMID: 12752783
- CsA-induced superoxide generation is causally involved in vasopressin type 1A receptor expression and low physiological concentrations of radicals are able to directly affect cellular signaling to increase Avpr1a expression in aortic smooth muscle cells. PMID: 12923165
- Ca(2+) increase induced by vasopressin was correlated with the number of V1a receptors. PMID: 12971956
- No significant changes either in V(1a) receptor mRNA or protein levels were observed in pregnancy suggesting variations in the hypothalamic V(1a) receptor expression levels alone cannot account for the endogenous antipyresis observed at term PMID: 14552875
- that the V(1a) receptor is increased at protein and mRNA level during development of hypertension in SHR rats but is normalized when hypertension is established. PMID: 15075196
- during specific physiological states, pituicyte V(1a) receptor activation modulates the release of neurohypophysial hormones. PMID: 15089968
- V(1a)-mediated arginine-vasopressin actions may influence LHRH release via cells in the immediate vicinity of LHRH neurones and/or via oestrogen-regulated cells in the anteroventral periventricular nucleus. PMID: 15189327
- A vasopressinergic pathway projects to the lateral area of the ventrolateral medulla (VLM) and modulates cardiopulmonary functions via AVP V1A receptors on neurons within the lateral VLM. PMID: 15239592
- AVP acts through V1a receptors and is involved in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats PMID: 15241560
- Rats with experimental renovascular hypertension manifest significantly higher expression of V1aR mRNA in the preoptic brain region in comparison to sham operated rats. PMID: 15613739
- V(1a) vasopressin receptor binding in several forebrain areas seems to be affected by brief periods of social interactions, and, in the lateral septum, it also appears to be related to dominance status. PMID: 16154572
- altered reactivity to V1A of V1 receptor in the superior mesenteric and/or hindquarter vascular regions of SHR PMID: 16398053
- The results provide evidence for enhanced engagement of the brain V1 VP receptors in regulation of resting MABP and in generation of exaggerated cardiovascular responses to air jet stress during the post-infarct state. PMID: 16423716
- Our findings demonstrate the importance of vasopressin acting on spinal V(1a) receptors for mediating sympathoexcitatory response to acute salt loading. PMID: 16873404
- Expression of the V(2)R is downregulated via V(1a)R pathway in LLC-PK(1)/rV(1a)R cells, and expression of V(2)R is downregulated by PMA-induced PKC pathway and upregulated by cAMP-PKA pathway. PMID: 17213462
- renal collecting duct cells Arginine-vasopressin selectively activates, via a complex of V1 and V2 receptor-mediated actions PMID: 17762181
- Modulation by vasopressin of the lateral septal circuitry may be part of the neuronal mechanism by which the peptide, acting via V(1A) receptors, promotes social recognition. PMID: 17970727
- Results show that both Avpr1a and b are involved in anxiety-related responses, and suggest that different fear responses are under the control of specific AVP receptor systems within discrete parts of the hippocampus. PMID: 18508119
- Oxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors. PMID: 18552879
- The counteractivity of V2R and V1aR could be required to maintain minimum urine volume in the dehydrated state PMID: 18701631
- findings support the concept that dendritic release of VP from magnocellular neurons within the PVN mediates, at least in part, the pressor response to ET(A) receptor activation at the SFO. PMID: 19258664
- Low pH stimulates vasopressin V2 receptor promoter activity and enhances downregulation induced by V1a receptor stimulation. PMID: 19587140
- V1/V2 Vasopressin receptor antagonism potentiates the renoprotection of renin-angiotensin system inhibition in rats with renal mass reduction. PMID: 19625993
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亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Located in cytoplasmic vesicles dispersed throughout the cell cytoplasm and to the plasma membrane.
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蛋白家族:G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily
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組織特異性:Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex.
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