BAI2 Antibody
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中文名稱:BAI2兔多克隆抗體
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貨號:CSB-PA066517
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規(guī)格:¥1100
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圖片:
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA066517(ADGRB2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA066517(ADGRB2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:ADGRB2 antibody; BAI2Adhesion G protein-coupled receptor B2 antibody; Brain-specific angiogenesis inhibitor 2 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse
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免疫原:Synthetic peptide of Human ADGRB2
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:1000-1:2000 IHC 1:25-1:100 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition.
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基因功能參考文獻(xiàn):
- These studies provide new insights into the signaling capabilities of the adhesion GPCR BAI2/ADGRB2 and shed light on how an apparent gain-of-function mutation to the receptor's C-terminus may lead to human disease. PMID: 28891236
- This is the first study reporting BAI2 as an interaction partner of GIP. PMID: 21787750
- BAI2 is a functional GPCR regulated by proteolytic processing and activates the NFAT pathway PMID: 20367554
- involvement of BAI2 in the ischemia-induced brain angiogenesis PMID: 12218411
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亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein.
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蛋白家族:G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
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組織特異性:Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
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數(shù)據(jù)庫鏈接:
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