BMPER Antibody, Biotin conjugated
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中文名稱:BMPER兔多克隆抗體, Biotin偶聯(lián)
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貨號(hào):CSB-PA839829LD01HU
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) BMPER Polyclonal antibody
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Uniprot No.:
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基因名:BMPER
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別名:BMP binding endothelial regulator antibody; BMP binding endothelial regulator precursor protein antibody; BMP-binding endothelial regulator protein antibody; BMPER antibody; BMPER_HUMAN antibody; Bone morphogenetic protein binding endothelial cell precursor derived regulator antibody; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator antibody; CRIM3 antibody; Crossveinless 2 antibody; CV 2 antibody; CV2 antibody; hCV2 antibody; Protein crossveinless 2 antibody; Protein crossveinless-2 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human BMP-binding endothelial regulator protein (271-418AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Biotin
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.
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基因功能參考文獻(xiàn):
- Overexpression of BMPER remarkably enhanced BMP-2-induced osteogenic differentiation, while suppression of BMPER effectively inhibited this process both in vitro and in vivo. PMID: 29518774
- that BMPER-modulated BMP pathway activity regulates VE-cadherin expression and vascular barrier function PMID: 27995357
- BMPER variants associated with a novel, attenuated subtype of diaphanospondylodysostosis. PMID: 26467725
- BMPER-dependent pathway involved in high glucose induced alkaline phosphatase expression in vascular smooth muscle cells. PMID: 26264461
- The proangiogenic BMPER effect in endothelial cells is mediated by inhibition of antiangiogenic thrombospondin-1 and enhanced expression and activation of the FGF signaling pathway that is crucial in the promotion of angiogenesis. PMID: 25503991
- BMPER is a novel regulator of the osteoblast-like differentiation of HCASMCs. PMID: 22778264
- Bmper is a critical regulator of Bmp-mediated vascular inflammation and that the fine-tuning of Bmp and Bmper levels is essential in the maintenance of normal vascular homeostasis. PMID: 22772758
- The data unequivocally demonstrated that BMPER is highly expressed in malignant tumors and that the growth of lung, colon, and uterine carcinomas is dependent on the presence of BMPER. PMID: 22020334
- Mutual regulation by BMP-9 and CV2 is essential in regulating the development of the vascular endothelium. PMID: 22474252
- Diaphonospondylodysostosis is caused by loss of BMPER function. PMID: 21990102
- BMPER-mediated signaling plays an essential role in vertebral segmentation early in human development, while defects in BMPER produce Diaphanospondylodysostosis. PMID: 20869035
- BMPER is a novel BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, and may play a role in endothelial cell differentiation by modulating local BMP activity PMID: 12897139
- Crossveinless-2 is an inhibitor of BMP function PMID: 14766204
- BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis. PMID: 18787191
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相關(guān)疾病:Diaphanospondylodysostosis (DSD)
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亞細(xì)胞定位:Secreted.
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組織特異性:Highly expressed in lung, and brain and also in primary chondrocytes.
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數(shù)據(jù)庫(kù)鏈接:
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