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CCDC170 Antibody, HRP conjugated

  • 中文名稱：
    CCDC170兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA815585LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CCDC170 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CCDC170
  • 別名：
    bA282P11.1 antibody; CC170_HUMAN antibody; CCDC170 antibody; Chromosome 6 open reading frame 97 antibody; Coiled coil domain containing protein C6orf97 antibody; Coiled-coil domain-containing protein 170 antibody; FLJ23305 antibody; Hypothetical protein LOC80129 antibody; LOC80129 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Coiled-coil domain-containing protein 170 protein (574-651AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in Golgi-associated microtubules organization and stabilization.
  • 基因功能參考文獻(xiàn)：
    1. Findings demonstrate that CCDC170 plays an essential role in Golgi-associated microtubules organization and stabilization, and implicate a mechanism for how perturbations in the CCDC170 gene may contribute to the hallmark changes in cell polarity and motility seen in breast cancer. PMID: 28687497
    2. Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients. PMID: 25370037
    3. Our findings suggest that ESR1 and C6orf97 gene polymorphism is associated with fracture and vertebral fracture risk in Chinese postmenopausal women. PMID: 24481879
    4. ESR1-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor-positive breast cancers PMID: 25099679
    5. Variation in rs3757318 of C6orf97 is associated with breast cancer risk. PMID: 25338983
    6. SNPs associated with breast cancer differ for Asian, European, and African ancestry groups PMID: 20661439

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  • 亞細(xì)胞定位：
    Golgi apparatus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21177

    KEGG: hsa:80129

    STRING: 9606.ENSP00000239374

    UniGene: Hs.660044