CD200 Antibody
-
中文名稱:CD200兔多克隆抗體
-
貨號(hào):CSB-PA005858
-
規(guī)格:¥880
-
圖片:
-
其他:
產(chǎn)品詳情
-
Uniprot No.:
-
基因名:
-
別名:CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD antigen CD200
-
宿主:Rabbit
-
反應(yīng)種屬:Human
-
免疫原:Synthesized peptide derived from the Internal region of Human CD200.
-
免疫原種屬:Homo sapiens (Human)
-
標(biāo)記方式:Non-conjugated
-
抗體亞型:IgG
-
純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產(chǎn)品提供形式:Liquid
-
應(yīng)用范圍:WB, ELISA
-
推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:20000 -
Protocols:
-
儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
-
基因功能參考文獻(xiàn):
- overexpression of human CD200 in donor pigs could constitute a promising strategy for overcoming xenograft rejection. PMID: 28968355
- Our results support the fact that CD200 can be added to routine Chronic lymphoproliferative disorders panel as it is useful in subcategorizing them. However, inclusion of CD20 ABC to routine panel does not seem plausible but may be done for difficult diagnostic cases or where anti-CD20 therapy is planned. PMID: 29567884
- A diligent morphological examination to look for the presence of hairy cells along with flow cytometric immunophenotyping showing consistent bright expression of CD200, in addition to well-described characteristic immunophenotype, helps in correctly diagnosing the case. This can be further confirmed by the consistent presence of V600E point mutation in BRAF gene. PMID: 30197362
- CD200(+) and/or CD56(+) positive expression in B-ALL patients at diagnosis is a poor prognostic biomarker. PMID: 29161980
- CD200 was expressed in 97.3% of atypical chronic lymphocytic leukemia cases, whereas it was dimly expressed in only 6.1% of mantle cell lymphoma cases. PMID: 28713070
- CD200 and/or CD56 positive expression in B-ALL at diagnosis suggest a poor prognosis and may be associated with biological aggressiveness. PMID: 29144828
- downregulation of CD200 expression resulted in an imbalance of increased Th1 cytokine and decreased Th2 cytokine production in placental trophoblasts in preeclampsia PMID: 28940677
- This is the first report of CD200 mRNA and protein expression in patients with transitional cell carcinoma of the human bladder. TCC tissues showed significantly higher CD200 expression than normal bladder tissues. CD200 signals were also higher in metastasized compared to localized TCC. The data provide a strong indication for a putative role of CD200 in the immune-evasion of bladder cancer. PMID: 29715095
- Our data confirm a negative impact of ABCG2 and CD200 overexpression also in AML patients considered at favorable risk according to ELN cytogenetic/molecular classification. PMID: 28618016
- Residual CD200 activity may prevent completion of abortions via induction of Treg cells. In chronic histiocytic intervillositis, infiltrating maternal effector T cells may block Treg induction. An autocrine role for CD200-CD200R interaction versus inhibition of soluble CD200 by soluble CD200R is discussed. PMID: 28326648
- patients with Autosomal dominant polycystic kidney disease have activated soluble CD200 levels which were related to renal function and inflammation. PMID: 28179401
- correlation of sCD200 serum levels with COPD-related parameters in humans with established disease revealed that the CD200/CD200R axis may be mechanistically linked to the disease course in COPD patients. PMID: 27864635
- It suppresses macrophage-mediated xenogeneic cytotoxicity and phagocytosis. PMID: 28573328
- High expression of CD200 is associated with chronic lymphocytic leukemia. PMID: 26910908
- It is a anti-inflammatory protein. PMID: 28390825
- CD200 expression therefore may be used to help identify pulmonary small cell carcinoma in flow cytometry specimens. PMID: 26584149
- Our data suggest a negative impact of CD200 expression in cytogenetically-normal acute myeloid leukemia PMID: 28407515
- CD200 was expressed in 87% of the neuroendocrine neoplasms studied. CD200 is a relatively sensitive marker of neuroendocrine neoplasms and represents a potential therapeutic target in these difficult-to-treat malignancies. PMID: 28821198
- Up-regulation of CD200 in MDS predicts poor prognosis. PMID: 28152413
- this study shows that that CD200 suppresses the immune system's response to vaccines, and that blocking CD200 could improve the efficacy of cancer immunotherapy PMID: 27485078
- These results suggest that CD200S activates TAMs to become DC-like antigen presenting cells, leading to the activation of CD8(+) cytotoxic T lymphocytes, which induce apoptotic elimination of tumor cells. PMID: 27108386
- increased expression of CD200, expansion of suppressive Treg cells and elevation of cytokines might have a role in multiple myeloma progression PMID: 26033514
- In the present study, we showed for the first time a correlation between CD200 expression and the Wnt signaling pathway in colon cancer cells. PMID: 27574016
- data confirms that a functionally active CD200 extracellular moiety can be cleaved from the surface of CD200 expressing cells following ectodomain shedding PMID: 27111430
- CD200 is a poor prognostic factor for overall survival in multiple myeloma (MM) patients. Bone marrow CD3 lymphocytes from MM patients express CD200 protein in higher proportion than healthy donors. PMID: 26177431
- CD200 expression by cultured cultured bone marrow mesenchymal stem cells can be induced by both osteogenic and pro-inflammatory cytokines through the sole NF-kappaB pathway. PMID: 26773707
- suggest that microglial activation may be partially caused by CD47/signal regulatory protein-alpha- and CD200/CD200R-mediated reductions in the immune inhibitory pathways PMID: 27095555
- CD200 is up-regulated and may be a novel biomarker for the prognosis in cutaneous squamous cell carcinoma. PMID: 27035797
- CD200 expression is a useful marker for evaluation of the severity of PCM and that lack of CD200 expression may improve the sensitivity of PCM to therapy with new drugs. PMID: 26763359
- the combination of CD200 and CD148 may have a potential differential diagnostic value in leukemic B-CLPDs, especially between CLL and MCL. PMID: 25791119
- CD200-CD200R1 signaling may be required for human pregnancy success. PMID: 26123445
- CD200 signaling may play a key role in regulating macrophage polarization toward anti-inflammatory phenotypes PMID: 26670206
- Suggest CD200 as both prognostic factor and potential therapeutic target AML, aiming to reverse the "do not eat me" signal of CD200 or to manipulate the suppressive immune microenvironment induced by CD200 binding to its receptor. PMID: 26338961
- CD160 and CD200 are expressed in B cells in chronic lymphocytic leukemia and are absent in other mature B-cell neoplasms. PMID: 25470765
- our study confirms that CD200/BTLA deletions are recurrent genetic lesions in the biology of BCP-ALL PMID: 26137961
- CD200 antigen expression features response for chemoradiation in patients squamous cell head and neck cancer. PMID: 24700450
- CD200 expression by early-stage human breast cancer cells in primary tumors did not correlate with increased regional lymph node metastasis. PMID: 25041579
- The proportion of CD200+ cells in PBMCs, peripheral CD14+ cells and CD4+ T cells was significantly lower in rheumatoid arthritis patients compared to controls, whereas the number of CD200+ cells was higher in synovium from RA patients than from controls. PMID: 25261692
- Prognostic value of CD200 detected in malignant ascites from patients with metastatic ovarian, endometrial and breast neoplasms remains to be elucidated. PMID: 25778329
- We demonstrate a significant correlation between CD200R1 positive cells and disease severity in rheumatoid arthritis (RA) patients, thus indicating the relevance of the CD200/CD200R1 signaling pathway potential involvement in the pathogenesis of RA. PMID: 24496593
- The mechanism underlying ESA might be associated with enhanced expression of CD200 and CD200R in the trophoblast, leading to an upregulation of the immune response during the first trimester of pregnancy. PMID: 25145957
- The results expand the understanding of the CD200 expression in mature B-cell neoplasms , giving further support for the inclusion of this marker in the routine investigation by flow cytometry. PMID: 24243815
- staining by flow cytometry can be useful in the differential diagnosis of B-cell neoplasms and in their detection in the bone marrow PMID: 25389338
- CD200 is expressed in a majority of plasma cell myeloma cases, and the expression is stable during the treatment process. PMID: 24958785
- The soluble OX-2 levels of type 2 diabetic foot were compared with that of healthy controls. PMID: 24964809
- The expression of CD200 as well as B7-H4 co-stimulatory molecules on CD14(+) cells were significantly higher in cord blood when compared with peripheral blood. PMID: 23066977
- Measurement of sCD200 and/or sCD200R1 may prove a useful and rapid means of monitoring subjects at risk of bone loss. PMID: 24333170
- expression of CD200 in the bone marrow of chronic lymphocytic leukemia PMID: 24405602
- [review] Inhibitory receptors are separated into two major classes based on their extracellular domains: immunoglobulin (Ig) and carbohydrate-binding C-type lectin families. PMID: 24388216
- Soluble CD200 might play a role in immune response in the pathogenesis of autoimmune and inflammatory skin disorders. PMID: 24157657
顯示更多
收起更多
-
亞細(xì)胞定位:Cell membrane; Single-pass type I membrane protein.
-
數(shù)據(jù)庫(kù)鏈接:
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-