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CDC42EP5 Antibody

  • 中文名稱：
    CDC42EP5兔多克隆抗體
  • 貨號：
    CSB-PA001512
  • 規(guī)格：
    ￥880
  • 圖片：
    • Western Blot analysis of Jurkat cells using Cdc42EP5 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CDC42EP5
  • 別名：
    CDC42EP5 antibody; BORG3 antibody; CEP5 antibody; Cdc42 effector protein 5 antibody; Binder of Rho GTPases 3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Cdc42EP5.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42.
  • 基因功能參考文獻：
    1. Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. PMID: 27913681
  • 亞細胞定位：
    Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    BORG/CEP family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17408

    OMIM: 609171

    KEGG: hsa:148170

    STRING: 9606.ENSP00000301200

    UniGene: Hs.415791