CDK19 Antibody
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中文名稱:CDK19兔多克隆抗體
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貨號(hào):CSB-PA945984
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規(guī)格:¥1100
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圖片:
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA945984(CDK19 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA945984(CDK19 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA945984(CDK19 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:CDK19
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別名:bA346C16.3 antibody; CDC2 related protein kinase 6 antibody; CDC2-related protein kinase 6 antibody; CDC2L6 antibody; CDK11 antibody; Cdk19 antibody; CDK19_HUMAN antibody; CDK8 like cyclin dependent kinase antibody; Cell division cycle 2 like 6 (CDK8 like) antibody; Cell division cycle 2 like protein kinase 6 antibody; Cell division cycle 2-like protein kinase 6 antibody; Cell division protein kinase 19 antibody; Cyclin dependent kinase (CDC2 like) 11 antibody; Cyclin dependent kinase 11 antibody; Cyclin dependent kinase 19 variant 2 antibody; Cyclin-dependent kinase 11 antibody; Cyclin-dependent kinase 19 antibody; Death preventing kinase antibody; Death-preventing kinase antibody; KIAA1028 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse
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免疫原:Synthetic peptide of Human CDK19
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:10000 WB 1:500-1:2000 IHC 1:100-1:300 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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基因功能參考文獻(xiàn):
- Genes coregulated by CDK8/19 and NFkappaB include IL8, CXCL1, and CXCL2. PMID: 28855340
- Moreover, it identified CDK19 and CDK8 to be specifically overexpressed during prostate cancer progression, highlighting their potential as novel therapeutic targets in advanced prostate cancer. PMID: 27678455
- High CDK19 expression is associated with osteosarcoma. PMID: 28416637
- On stimulation of TLR9, CDK8/19 positively regulates inflammatory gene transcription in cooperation with NF-kappaB and C/EBPbeta. PMID: 28151579
- Data suggest that, during neurogenesis, Mediator complex cyclin-dependent kinases (CDK8, CDK19) interact directly with PRC2 (polycomb repressive complex 2) subunit EZH2 (enhancer of zeste homolog 2), as well as SUZ12 (suppressor of zeste 12 homolog). PMID: 26002960
- Mediator-associated kinases CDK8 and CDK19 restrain increased activation of key super-enhancer-associated genes in acute myeloid leukaemia (AML) cells PMID: 26416749
- Microarrays identified target genes for each CDK, and we selected six genes: two target genes of CDK8, two target genes of CDK19 and two genes that were targets for both. PMID: 22117896
- CDK8 and CDK19, individually interact with PRMT5 and WDR77, and their interactions with PRMT5 cause transcriptional repression of C/EBPbeta target genes. PMID: 23749998
- plays a role in mechanisms of transcriptional regulation upon protein phosphorylation. (review) PMID: 20408451
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亞細(xì)胞定位:Cytoplasm. Cytoplasm, perinuclear region. Nucleus.
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蛋白家族:Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
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數(shù)據(jù)庫(kù)鏈接:
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