CIB2 Antibody
-
中文名稱:CIB2兔多克隆抗體
-
貨號:CSB-PA089401
-
規(guī)格:¥2024
-
圖片:
-
其他:
產品詳情
-
產品名稱:Rabbit anti-Homo sapiens (Human) CIB2 Polyclonal antibody
-
Uniprot No.:
-
基因名:CIB2
-
宿主:Rabbit
-
反應種屬:Human,Mouse
-
免疫原:Synthesized peptide derived from internal of Human CIB2.
-
免疫原種屬:Homo sapiens (Human)
-
克隆類型:Polyclonal
-
純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度:It differs from different batches. Please contact us to confirm it.
-
產品提供形式:Liquid
-
應用范圍:ELISA,IHC
-
推薦稀釋比:
Application Recommended Dilution IHC 1:50-1:100 -
Protocols:
-
儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關產品
靶點詳情
-
功能:Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.
-
基因功能參考文獻:
- this study identifies CIB1 and CIB2 as host helper factors for HIV-1 replication that are required for optimal receptor-mediated viral entry PMID: 27489023
- results suggest that GJB2 and CIB2 are common cause of hearing loss in different Pakistani ethnicities PMID: 29086887
- High CIB2 expression is associated with ovarian Cancer. PMID: 28729416
- Novel homozygous missense variant c.196C>T and compound heterozygous variants, c.[97C>T];[196C>T], were associated with nonsyndromic deafness. PMID: 26173970
- We identified a novel variant (rs7164338) on chromosome 15q25.1 in the CIB2 associated with lower pulse wave velocity. PMID: 26378684
- CIB2 (Calcium and Integrin Binding Protein 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic Family PMID: 26426422
- Data indicate that that CIB2 localizes to stereocilia and interacts with the USH proteins myosin VIIa and whirlin, suggesting CIB2 is a Ca2+-buffering protein essential for calcium homeostasis in the mechanosensory stereocilia of inner ear hair cells. PMID: 24022220
- Consistent with molecular modeling predictions of calcium binding, CIB2 significantly decreased the ATP-induced calcium responses in heterologous cells, whereas mutations in deafness DFNB48 altered CIB2 effects on calcium responses PMID: 23023331
- CIB2, as binding partners for the integrin alphaIIb subunit, which suggests that they are potentially involved in regulating integrin alphaIIb subunit activation. PMID: 22779914
顯示更多
收起更多
-
相關疾?。?/div>Deafness, autosomal recessive, 48 (DFNB48); Usher syndrome 1J (USH1J)亞細胞定位:Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma.組織特異性:Widely expressed.數(shù)據(jù)庫鏈接:
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-