CLCN6 Antibody
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中文名稱:CLCN6兔多克隆抗體
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貨號:CSB-PA005485LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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IHC image of CSB-PA005485LA01HU diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
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Immunofluorescence staining of U251 cells with CSB-PA005485LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) CLCN6 Polyclonal antibody
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Uniprot No.:
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基因名:CLCN6
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別名:Chloride channel 6 antibody; Chloride channel protein 6 antibody; Chloride channel voltage sensitive 6 antibody; Chloride transport protein 6 antibody; ClC 6 antibody; ClC-6 antibody; ClC6 antibody; CLCN6 antibody; CLCN6_HUMAN antibody; KIAA0046 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Chloride transport protein 6 protein (572-869AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,CLCN6 Antibody (CSB-PA005485LA01HU),的標(biāo)記方式是Non-conjugated。對于CLCN6 Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, IHC, IF
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推薦稀釋比:
Application Recommended Dilution IHC 1:200-1:500 IF 1:100-1:500 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.
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基因功能參考文獻(xiàn):
- These findings implicate the effect of rare coding variants in CLCN6 in Blood Pressure variation and offer new insights into Blood Pressure regulation. PMID: 26658788
- A non-synonymous single nucleotide variation (SNV) was identified in the voltage-sensitive chloride channel 6 gene. PMID: 25794116
- late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression PMID: 20466723
- differential sorting of endogenous (late endosomal) versus overexpressed (early and recycling endosomal) ClC-6 is reminiscent of that of other late endosomal/lysosomal membrane proteins PMID: 17534424
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亞細(xì)胞定位:Endosome membrane; Multi-pass membrane protein. Note=Detected in detergent-resistant lipid rafts.
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蛋白家族:Chloride channel (TC 2.A.49) family, ClC-6/CLCN6 subfamily
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組織特異性:Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
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數(shù)據(jù)庫鏈接:
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