CNTNAP1 Antibody
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中文名稱(chēng):CNTNAP1兔多克隆抗體
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貨號(hào):CSB-PA005692LA01HU
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規(guī)格:¥440
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促銷(xiāo):
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱(chēng):Rabbit anti-Homo sapiens (Human) CNTNAP1 Polyclonal antibody
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Uniprot No.:
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基因名:CNTNAP1
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別名:Caspr antibody; Caspr1 antibody; CNTNAP antibody; Cntnap1 antibody; CNTP1_HUMAN antibody; Contactin associated protein 1 antibody; Contactin-associated protein 1 antibody; MHDNIV antibody; NCP1 antibody; Neurexin 4 antibody; Neurexin IV antibody; Neurexin-4 antibody; Nrxn4 antibody; p190 antibody; Paranodin antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Contactin-associated protein 1 protein (26-356AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁(yè)面中的產(chǎn)品,CNTNAP1 Antibody (CSB-PA005692LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于CNTNAP1 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:
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克隆類(lèi)型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, IHC
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推薦稀釋比:
Application Recommended Dilution IHC 1:20-1:200 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
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基因功能參考文獻(xiàn):
- E. coli exploits Caspr1 as a host receptor for penetration of the blood-brain barrier, resulting in meningitis PMID: 29895952
- In two brothers with severe congenital hypotonia and foot deformities, we identified compound heterozygous variants in CNTNAP1, reporting the first causative missense variant, p.(Cys323Arg). Motor nerve conductions were markedly decreased. PMID: 27782105
- CNTNAP1 mutations were found to induce characteristic ultrastructural lesions of the paranodal region. PMID: 27818385
- report a consanguineous Arab family from Qatar with three children having an early lethal form of arthrogryposis multiplex congenita and a novel frameshift mutation in CNTNAP1 PMID: 28254648
- Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects PMID: 24319099
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相關(guān)疾?。?/div>Lethal congenital contracture syndrome 7 (LCCS7)亞細(xì)胞定位:Membrane; Single-pass type I membrane protein. Cell junction, paranodal septate junction.蛋白家族:Neurexin family組織特異性:Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis.數(shù)據(jù)庫(kù)鏈接:
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