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COQ7 Antibody

  • 中文名稱:
    COQ7兔多克隆抗體
  • 貨號:
    CSB-PA005806GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    COQ7
  • 別名:
    COQ7 antibody; 5-demethoxyubiquinone hydroxylase antibody; mitochondrial antibody; DMQ hydroxylase antibody; EC 1.14.13.- antibody; Timing protein clk-1 homolog antibody; Ubiquinone biosynthesis monooxygenase COQ7 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human COQ7
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能:
    Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
  • 基因功能參考文獻:
    1. cCOQ7 COQ7 vCOQ7 PMID: 28409910
    2. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. PMID: 25339443
    3. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1. PMID: 18927074
    4. The siRNA-mediated knock down leads to an increase in cytoplasmic superoxide dismutase (SOD1) mRNA levels and activity PMID: 19135146
  • 相關(guān)疾?。?/div>
    Coenzyme Q10 deficiency, primary, 8 (COQ10D8)
  • 亞細胞定位:
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族:
    COQ7 family
  • 組織特異性:
    Expressed dominantly in heart and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2244

    OMIM: 601683

    KEGG: hsa:10229

    STRING: 9606.ENSP00000322316

    UniGene: Hs.157113