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DNTTIP1 Antibody, HRP conjugated

  • 中文名稱：
    DNTTIP1兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA007089LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DNTTIP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DNTTIP1
  • 別名：
    C20orf167 antibody; Deoxynucleotidyltransferase terminal interacting protein 1 antibody; Deoxynucleotidyltransferase terminal-interacting protein 1 antibody; dJ447F3.4 antibody; DNTTIP1 antibody; TdIF 1 antibody; TdIF1 antibody; TDIF1_HUMAN antibody; TdT binding protein antibody; TdT interacting factor 1 antibody; TdT-interacting factor 1 antibody; Terminal deoxynucleotidyltransferase interacting factor 1 antibody; Terminal deoxynucleotidyltransferase-interacting factor 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Deoxynucleotidyltransferase terminal-interacting protein 1 protein (1-329AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
  • 基因功能參考文獻：
    1. In luciferase assays, TdIF1 can up-regulate transcription activity of the promoters containing the TdIF1-binding sequences, and this effect is mainly through the palindrome 5'-TGCATG-3'. PMID: 25619743
    2. During cell division, DNTTIP1 is part of the mitotic deacetylase complex MIDAC, which also contains C14ORF43/MIDEAS and HDAC1/HDAC2. PMID: 21258344
    3. During cell division, DNTTIP1 forms a complex with C14ORF43/MIDEAS and HDAC1/HDAC2. PMID: 21258344
    4. The TdT binding, DNA binding and dimerization regions, and nuclear localization signal (NLS) in TdIF1, were identified. PMID: 17663723
  • 亞細胞定位：
    Nucleus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16160

    OMIM: 611388

    KEGG: hsa:116092

    STRING: 9606.ENSP00000361705

    UniGene: Hs.472852