DYNC1LI2 Antibody
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中文名稱:DYNC1LI2兔多克隆抗體
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貨號:CSB-PA007296GA01HU
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規(guī)格:¥3,900
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:DYNC1LI2
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別名:Cytoplasmic dynein 1 light intermediate chain 2 antibody; cytosolic antibody; DC1L2_HUMAN antibody; DNCLI2 antibody; Dync1li2 antibody; Dynein cytoplasmic 1 light intermediate chain 2 antibody; Dynein light intermediate chain 2 antibody; dynein light intermediate chain 2 cytosolic antibody; dynein; cytoplasmic; light intermediate polypeptide 2 antibody; LIC-2 antibody; LIC2 antibody; LIC53/55 antibody; OTTHUMP00000174820 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse,Rat
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免疫原:Human DYNC1LI2
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免疫原種屬:Homo sapiens (Human)
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抗體亞型:IgG
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純化方式:Antigen Affinity purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
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基因功能參考文獻:
- Cortically localized dynein, essential for maintaining correct spindle orientation, consists majorly of LIC2-dynein, which interacts with cortical 14-3-3 epsilon- zeta and Par3, conserved proteins required for orienting the spindle. PMID: 28003657
- This study uncovers a novel functional hierarchy during mitotic checkpoint inactivation between the closely related but homologous LIC subunits of cytoplasmic dynein. PMID: 27441562
- although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle. PMID: 25422374
- using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway. PMID: 21169557
- FIP3 was identified as the first membrane-associated interacting-partner for DLIC-2. PMID: 20214888
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亞細胞定位:Cytoplasm, cytoskeleton.
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蛋白家族:Dynein light intermediate chain family
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數(shù)據(jù)庫鏈接:
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