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  4. EDC4 Antibody, FITC conjugated

EDC4 Antibody, FITC conjugated

  • 中文名稱：
    EDC4兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA744034LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EDC4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    autoantigen antibody; Autoantigen Ge 1 antibody; Autoantigen Ge-1 antibody; Autoantigen Ge1 antibody; Autoantigen RCD 8 antibody; Autoantigen RCD-8 antibody; Autoantigen RCD8 antibody; edc4 antibody; EDC4_HUMAN antibody; Enhancer of mRNA decapping 4 antibody; Enhancer of mRNA-decapping protein 4 antibody; Ge 1 antibody; Hedls antibody; Human enhancer of decapping large subunit antibody; RCD 8 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Enhancer of mRNA-decapping protein 4 protein (753-952AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產品評價

靶點詳情

  • 功能：
    In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).
  • 基因功能參考文獻：
    1. EDC4 plays a key role in homologous recombination by stimulating end resection at double-strand breaks. PMID: 29511213
    2. The assembly of EDC4 and Dcp1a into processing bodies is critical for the translational regulation of IL-6. PMID: 25970328
    3. EDC4 is a processing body (P-body) component. PMID: 24858563
    4. The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells. PMID: 24510189
    5. EDC4 might contribute to regulation of CoA biosynthesis in addition to its scaffold function in processing bodies PMID: 22982864

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  • 亞細胞定位：
    Cytoplasm, P-body. Nucleus.
  • 蛋白家族：
    WD repeat EDC4 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17157

    OMIM: 606030

    KEGG: hsa:23644

    STRING: 9606.ENSP00000351811

    UniGene: Hs.75682