ELF3 Antibody, Biotin conjugated

1. ELF3 was demonstrated to form a positive feedback loop with MAPK pathways. PMID: 30365150
2. Low ESE1 expression is associated with Nonsmall cell lung cancer. PMID: 30015943
3. Data suggest that ELF3 is up-regulated at mRNA and protein levels in NSCLC (non-small cell lung cancer) tissues compared to corresponding control lung tissue; expression level of ELF3 is correlated with overall survival of patients with NSCLC. PMID: 29208568
4. Leptin synergizes with IL-1beta in inducing ELF3 expression in chondrocytes. PMID: 29550824
5. Data proved the direct binding of miR-320a-3p on the 3'UTR region of ELF3 mRNA in non-small cell lung cancer cells, causing the decreasing expression of ELF3 transcriptionally. PMID: 29803922
6. Data suggest ESE-1 silencing as a mean to treat HER2(+) patients who show resistance to anti-HER2 therapy. PMID: 29187433
7. These findings position RIPK4 upstream of a hierarchal IRF6-GRHL3-ELF3 transcription factor pathway in keratinocytes. PMID: 27667567
8. Epithelium-specific ETS transcription factor 1 (ESE1), a member of the Ets transcription factor family. PMID: 28247944
9. ELF3 interacts directly with the HMG domain of Sox9. Importantly, overexpression of ELF3 significantly decreased Sox9/CBP-dependent HAT activity. PMID: 27310669
10. Data indicate that the transcription factor E74-like factor 3 (ELF3) was one of the genes whose expression was upregulated in microdissected ovarian cancer cells of long-term survivors. PMID: 28199976
11. ELF3 is a frequently mutated tumor suppressor gene of periampullary tumors. PMID: 26804919
12. ELF3 is a novel transcriptional repressor of estrogen receptor alpha in breast cancer cells. PMID: 26920025
13. suggest that ESE-1 may play a role in regulating airway inflammation by regulating ICAM-1 expression PMID: 26185364
14. our data suggested that ESE1/ELF3 may promote the UC progression via accelerating NF-kappaB activation and thus facilitating IEC apoptosis. PMID: 25926267
15. data suggest that polyomavirus enhancer activator 3 and epithelium-specific transcription factor-1 may play important roles in pluri potent and tumorigenic embryonic carcinoma cells. PMID: 24694612
16. data identify Elf3 as a pivotal driver for beta-catenin signaling in CRC, and highlight potential prognostic and therapeutic significance of Elf3 in CRC. PMID: 24874735
17. ESE-1 actS as an upstream effector to regulate OCT4 transcription in NCCIT pluripotent embryonic carcinoma cells. PMID: 24971534
18. The physical interaction between ELF3 and androgen receptor (AR) inhibits the recruitment of AR to specific androgen response elements within target gene promoters. PMID: 23435425
19. ELF3 is a candidate transcriptional regulator involved in human urothelial cytodifferentiation. PMID: 24374157
20. The concordant upregulation of ESE1/ELF3 and NF-kappaB in human prostate tumors. PMID: 23687337
21. Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes. PMID: 23329352
22. ELF3 and CEA expression showed statistically significant differences among four lymph node groups: lymph nodes from patients with colorectal cancer categorized into three Dukes' stages and LNs from patients with ulcerative colitis. PMID: 22993316
23. a novel role for ELF3 as a procatabolic factor that may contribute to cartilage remodeling and degradation by regulating MMP13 gene transcription. PMID: 22158614
24. ESE-1 contains signal sequences that play a critical role in regulating its subcellular localization and function, and that an intact SAR domain mediates mammary epithelial cell transformation exclusively in the cytoplasm PMID: 21871131
25. ErbB2 activation of ESX gene expression PMID: 12032832
26. ESX regulates HER2 expression by binding to DRIP130 PMID: 12242338
27. co-ordinate activation and binding of ESE-1, Sp1, and NF-kappaB to the MIP-3alpha promoter is required for maximal gene expression by cytokine-stimulated Caco-2 human intestinal epithelial cells. PMID: 12414801
28. Ese-1 binds with Skn-1a in human cells PMID: 12624109
29. ERT mediates the expression of TGF-beta RII, and the transcriptional inhibition of ets-related transcription factor could be a one of the mechanisms of colonic carcinogenesis PMID: 14582709
30. results support a role for the ETS factor ESE-1 as a novel transcriptional regulator of angiopoietin-1 gene regulation in the setting of inflammation PMID: 14715662
31. ESX expression alone confers a transformed and in vitro metastatic phenotype to otherwise normal MCF-12A cells PMID: 14767472
32. stably expressed green fluorescent protein-ESE-1 transforms MCF-12A human mammary epithelial cells; and the ESE-1 SAR domain, acting in the cytoplasm, is necessary and sufficient to mediate this transformation PMID: 15169914
33. the induction of claudin7 expression by ELF3 appears critical to the formation of the epithelial structures in biphasic synovial sarcoma PMID: 17060315
34. AT-hook domain, as well as serine- and aspartic acid-rich domain but not the pointed domain, is necessary for Elf3 activation of promoter activity. PMID: 17148437
35. ESE-1 functions are coordinately regulated by Pak1 phosphorylation and beta-TrCP-dependent ubiquitin-proteasome pathways. PMID: 17491012
36. Intracellular ESE-1 staining in chondrocytes in cartilage from patients with osteoarthritis, but not in normal cartilage, further suggests a fundamental role for ESE-1 in cartilage degeneration and suppression of repair. PMID: 18044710
37. ESE-1 negatively regulates the invasion of oral squamous cell carcinoma via transcriptional suppression of MMP-9. PMID: 18302674
38. ESE-1 and ESE-3 play an important role in airway inflammation. PMID: 18475289

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HGNC: 3318

OMIM: 602191

KEGG: hsa:1999

STRING: 9606.ENSP00000352673

UniGene: Hs.603657