Western blot
All lanes: ENOX1 antibody at 5µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Raji whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 74, 28 kDa
Observed band size: 74 kDa
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA007676LA01HU at dilution of 1:100
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貨期:
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Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.
基因功能參考文獻:
We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons. PMID: 23939472
These results indicate that this sequence variant in ENOX1 may contribute to the familial autoimmune myasthenia in these patients. PMID: 22744667
copper-binding capacity, enzymatic activity, and time-keeping (clock) properties PMID: 19055324
亞細胞定位:
Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
蛋白家族:
ENOX family
組織特異性:
Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of heal