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EPS8L2 Antibody

  • 中文名稱：
    EPS8L2兔多克隆抗體
  • 貨號：
    CSB-PA204841
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) EPS8L2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EPS8L2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human ES8L2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells.
  • 基因功能參考文獻：
    1. frame-shift variant (c.1014delC; p.Ser339Alafs*15) was identified in EPS8L2, encoding Epidermal growth factor receptor Pathway Substrate 8 L2, a protein of hair cells' stereocilia previously implicated in progressive deafness in the mouse PMID: 26282398
  • 相關疾?。?/div>
    Deafness, autosomal recessive, 106 (DFNB106)
  • 亞細胞定位：
    Cytoplasm. Cell projection, stereocilium.
  • 蛋白家族：
    EPS8 family
  • 組織特異性：
    Detected in fibroblasts and placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21296

    OMIM: 614988

    KEGG: hsa:64787

    STRING: 9606.ENSP00000320828

    UniGene: Hs.55016