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FAM19A4 Antibody, FITC conjugated

  • 中文名稱：
    FAM19A4兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA836253LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FAM19A4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FAM19A4
  • 別名：
    TAFA4 antibody; FAM19A4 antibody; Chemokine-like protein TAFA-4 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein FAM19A4 protein (36-140AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Modulates injury-induced and chemical pain hypersensitivity. Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release.
  • 基因功能參考文獻(xiàn)：
    1. Hypermethylation of FAM19A4/miR124-2 in the self-sample was tested in a quantitative methylation specific PCR and compared between lesions caused by HPV16/18 and other hrHPV genotypes. There were no differences in the percentages of positive FAM19A4/miR124-2 methylation assays between lesions caused by HPV16/18 (73.8% in CIN3+) or other hrHPV genotypes (66.7% in CIN3+) (p=0.538). PMID: 30219239
    2. With a similarly good clinical performance in both sample types, combined FAM19A4 methylation analysis and HPV16/18 genotyping provides a feasible triage strategy for hrHPV-positive women, with direct applicability on self-samples PMID: 27415009
    3. FAM19A4/mir124-2 methylation analysis performs equally well in HPV-positive lavage- and brush self-samples to identify women with CIN3+. In combination with HPV16/18 genotyping, significantly higher CIN3+ sensitivities are obtained, at decreased specificity. PMID: 26921784
    4. FAM19A4 is a novel ligand of formyl peptide receptor 1. PMID: 25109685
    5. among high risk HPV-positive women from an outpatient population aged >/= 30 years, methylation analysis of FAM19A4 is an attractive marker for the identification of women with high-grade cervical intraepithelial neoplasia and cervical cancer PMID: 26317579
    6. High methylation of FAM19A4 is associated with cervical carcinomas. PMID: 25281488

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    FAM19/TAFA family
  • 組織特異性：
    Expressed in brain. Expressed in LPS-stimulated monocytes and macrophages, especially in polarized M1.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21591

    OMIM: 617498

    KEGG: hsa:151647

    STRING: 9606.ENSP00000295569

    UniGene: Hs.187873