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FAM3A Antibody

  • 中文名稱：
    FAM3A兔多克隆抗體
  • 貨號(hào)：
    CSB-PA064607
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA064607(FAM3A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    FAM3A
  • 別名：
    2-19 antibody; 2.19 antibody; Cytokine-like protein 2-19 antibody; DLD antibody; DXS560S antibody; FAM3A antibody; FAM3A_HUMAN antibody; family with sequence similarity 3; member A antibody; Protein FAM3A antibody; XAP 7 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human FAM3A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May act as a defensin against invading fungal microorganisms.
  • 基因功能參考文獻(xiàn)：
    1. These results suggest that C/EBPbeta plays an important role in regulating FAM3A promoter activity and FAM3A inhibits adipocyte differentiation. PMID: 27688071
    2. In the present study, we report a putative human homologue of the antimicrobial Drosophila-derived drosomycin, designated drosomycin-like defensin (DLD), with specific antifungal activity. PMID: 18212107
    3. FAM3A plays crucial roles in the regulation of glucose and lipid metabolism in the liver, where it activates the PI3K-Akt signaling pathway by way of a Ca(2+) /CaM-dependent mechanism PMID: 24806753
    4. Upregulation of FAM3A by PPARgamma activation is correlated with increased pAkt level in liver cells PMID: 23562554
    5. Expressed prominently in the vascular endothelium, particularly capillaries, also in islets of Langerhans. PMID: 12160727

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    FAM3 family
  • 組織特異性：
    In similar amounts in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13749

    OMIM: 300492

    KEGG: hsa:60343

    STRING: 9606.ENSP00000352955

    UniGene: Hs.289108