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FASTKD1 Antibody

  • 中文名稱：
    FASTKD1兔多克隆抗體
  • 貨號：
    CSB-PA182654
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA182654(FASTKD1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    FASTKD1
  • 別名：
    FAKD1_HUMAN antibody; FAST kinase domain containing protein 1 antibody; FAST kinase domain-containing protein 1 antibody; FAST kinase domains 1 antibody; FASTKD1 antibody; FLJ21901 antibody; KIAA1800 antibody; OTTHUMP00000207008 antibody; OTTHUMP00000207010 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human FASTKD1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:100-1:300
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.
  • 基因功能參考文獻：
    1. Disruption of FASTKD1 increases ND3 mRNA level. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone. Each RAP domain of FASTK proteins contains a nuclease fold with a conserved aspartate residue at the putative active site. The RAP domain is essential for the function of the FASTK proteins, while the region upstream determines RNA targeting and protein localization. PMID: 28335001
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    FAST kinase family
  • 組織特異性：
    Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26150

    OMIM: 617529

    KEGG: hsa:79675

    UniGene: Hs.529276