FZD10 Antibody
-
中文名稱(chēng):FZD10兔多克隆抗體
-
貨號(hào):CSB-PA970487
-
規(guī)格:¥1100
-
圖片:
-
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA970487(FZD10 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
-
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA970487(FZD10 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
-
-
其他:
產(chǎn)品詳情
-
Uniprot No.:
-
基因名:
-
別名:FZD10; Frizzled-10; Fz-10; hFz10; FzE7; CD antigen CD350
-
宿主:Rabbit
-
反應(yīng)種屬:Human,Mouse
-
免疫原:Synthetic peptide of Human FZD10
-
免疫原種屬:Homo sapiens (Human)
-
標(biāo)記方式:Non-conjugated
-
抗體亞型:IgG
-
純化方式:Antigen affinity purification
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
-
產(chǎn)品提供形式:Liquid
-
應(yīng)用范圍:ELISA,IHC
-
推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:10000 IHC 1:50-1:200 -
Protocols:
-
儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能:Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
-
基因功能參考文獻(xiàn):
- there was a strong inverse correlation between nuclear immunostaining scores for beta-catenin expression and expression patterns of FZD10 PMID: 19134005
- FZD10 transactivation causes the activation of the Dvl-Rac1-JNK pathway and is associated with the development/progression of synovial sarcomas PMID: 19137009
-
亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein.
-
蛋白家族:G-protein coupled receptor Fz/Smo family
-
組織特異性:Highest levels in the placenta and fetal kidney, followed by fetal lung and brain. In adult brain, abundantly expressed in the cerebellum, followed by cerebral cortex, medulla and spinal cord; very low levels in total brain, frontal lobe, temporal lobe an
-
數(shù)據(jù)庫(kù)鏈接:
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-