GNAT2 Antibody, HRP conjugated
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中文名稱:GNAT2兔多克隆抗體, HRP偶聯(lián)
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貨號(hào):CSB-PA009599LB01HU
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) GNAT2 Polyclonal antibody
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Uniprot No.:
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基因名:GNAT2
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別名:ACHM4 antibody; Cone type transducin alpha subunit antibody; GNAT 2 antibody; GNAT C antibody; Gnat2 antibody; GNAT2_HUMAN antibody; GNATC antibody; Guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 2 antibody; Guanine nucleotide binding protein G t subunit alpha 2 antibody; Guanine nucleotide-binding protein G(t) subunit alpha-2 antibody; Transducin alpha 2 antibody; Transducin alpha-2 chain antibody; Transducin alpha2 antibody; Transducin cone specific alpha polypeptide antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Guanine nucleotide-binding protein G(t) subunit alpha-2 protein (2-139AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:HRP
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
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基因功能參考文獻(xiàn):
- The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (p.T383fsX and p.T296YfsX9) and three in CNGA3 (p.R283Q, p.R427C and p.L527R). PMID: 23362848
- Single nucleotide polymorphisms in GNAT2 gene is associated with obesity. PMID: 23563607
- Missense mutations, nonsense mutations, splice mutations, and small deletions and insertions in the affected genes cause achromatopsia. PMID: 21267001
- Expression of GNAT2 transgene, when found in rod photoreceptor cells rather than in cones, demonstrates different mechanisms of amplification in the body's G-protein alpha cascades and the activation of phosphodiesterase 6. PMID: 20603337
- Clinical and genetic investigation of a large Tunisian family with complete achromatopsia: identification of a new nonsense mutation in GNAT2 gene. PMID: 21107338
- mutations in GNAT2 are implicated in achromatopsia PMID: 12077706
- We detected a deletion of a highly conserved lysine at codon 270 in a critical functional area of the alpha-cone transducin molecule, and therefore is not the disease causing mutation. PMID: 15094710
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相關(guān)疾?。?/div>Achromatopsia 4 (ACHM4)亞細(xì)胞定位:Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.蛋白家族:G-alpha family, G(i/o/t/z) subfamily組織特異性:Retinal rod outer segment.數(shù)據(jù)庫(kù)鏈接:
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