GNG2 Antibody
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中文名稱:GNG2兔多克隆抗體
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貨號:CSB-PA164096
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規(guī)格:¥1100
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圖片:
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA164096(GNG2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA164096(GNG2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, mouse brain tissue, Primary antibody: CSB-PA164096(GNG2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:G gamma I antibody; G gamma-I antibody; GBG2_HUMAN antibody; GNG 2 antibody; Gng2 antibody; Guanine nucleotide binding protein gamma 2 antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse
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免疫原:Fusion protein of Human GNG2
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
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基因功能參考文獻(xiàn):
- High GNG2 expression is associated with alcoholic hepatitis. PMID: 28818508
- G-protein betagamma subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity. PMID: 25941381
- Alteration of gene expression profiling including GPR174 and GNG2 is associated with vasovagal syncope. PMID: 25367286
- Data indicate that endogenous mTOR interacts with Gbetagamma. PMID: 24462769
- increased protein expression level of GNG2 alone inhibits proliferation of malignant melanoma cells in vitro and in vivo PMID: 23031273
- presence of Gng2 and Netrin-G2 immunoreactive elements in the insular cortex, but not in the putamen, suggests a possible common ontogeny of the claustrum and insula PMID: 22957104
- Gbetagamma inhibits Epac-induced Ca 2+ elevation in melanoma cells. Cross talk of Ca 2+ signaling between Gbetagamma & Epac plays a major role in melanoma cell migration. PMID: 21679469
- Data implicate the domain I-II linker region as an important contributor to voltage dependent Gbeta1/Ggamma2 modulation of Cav2.2 calcium channels. PMID: 20181083
- Data show that activation of PLCbeta(2) by alpha(q) and beta1gamma2 differ from activation by Rac2 and from each other. PMID: 20007712
- Data show that G protein inhibition of N-type calcium channels is critically dependent on two separate but adjacent approximately 20-amino acid regions of the Gbeta subunit, as examined with Gbetas 1 and 5 and Ggamma2. PMID: 15105422
- 10 genes were down-regulated following treatment of the T-ALL cells with 0.15 and 1.5 microg/mL of metal ores at 72 h PMID: 15747776
- Fission of transport carriers at the trans-Golgi network is dependent on specifically PLCbeta3, which is necessary to activate PKCeta and PKD in that Golgi compartment, via diacylglycerol production. PMID: 17492941
- signaling pathway by which G(i)-coupled receptor specifically induces Rac and Cdc42 activation through direct interaction of Gbetagamma with FLJ00018. PMID: 18045877
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亞細(xì)胞定位:Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族:G protein gamma family
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組織特異性:Expressed in fetal tissues, including testis, adrenal gland, brain, white blood cells and brain.
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數(shù)據(jù)庫鏈接:
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