Your Good Partner in Biology Research

GNG7 Antibody

  • 中文名稱(chēng):
    GNG7兔多克隆抗體
  • 貨號(hào):
    CSB-PA009619LA01HU
  • 規(guī)格:
    ¥440
  • 促銷(xiāo):
    小規(guī)格抗體限時(shí)一口價(jià)
  • 圖片:
    • Immunofluorescence staining of MCF-7 cells with CSB-PA009619LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) GNG7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    GNG7 antibody; GNGT7 antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 protein (2-65AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,GNG7 Antibody (CSB-PA009619LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于GNG7 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA009619LB01HU GNG7 Antibody, HRP conjugated ELISA
    FITC CSB-PA009619LC01HU GNG7 Antibody, FITC conjugated
    Biotin CSB-PA009619LD01HU GNG7 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.
  • 基因功能參考文獻(xiàn):
    1. GNG7 is a highly specific promoter methylated gene associated with head and neck cancer. PMID: 23403885
    2. Loss of GNG7 protein expression is a frequent event in head and neck cancer with hypermethylation of the promoter region of GNG7 being probably the mechanism for the observed inactivation. PMID: 22183866
    3. Reduced expression of G-gamma 7 is associated with the histological grade of EHCC and may prove to be a useful marker for predicting the prognosis of human EHCC. PMID: 20543539
    4. GNG7 suppression represents a new prognostic indicator in cases of oesophageal cancer. PMID: 18219292
  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族:
    G protein gamma family
  • 組織特異性:
    Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 4410

    OMIM: 604430

    KEGG: hsa:2788

    STRING: 9606.ENSP00000371594

    UniGene: Hs.515544