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GOLGA3 Antibody, Biotin conjugated

  • 中文名稱(chēng)：
    GOLGA3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA600096LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) GOLGA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GOLGA3Golgin subfamily A member 3 antibody; Golgi complex-associated protein of 170 kDa antibody; GCP170 antibody; Golgin-160 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Golgin subfamily A member 3 protein (217-405AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Golgi auto-antigen; probably involved in maintaining Golgi structure.
  • 基因功能參考文獻(xiàn)：
    1. The golgin-160 binds directly to the third intracellular loop of beta1AR and that this binding depends on three basic residues in this loop. PMID: 24566136
    2. Golgi protein golgin160 recruits dynein to Golgi membranes. PMID: 22814606
    3. A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic patient PMID: 20170975
    4. NH2 terminal domain of Golgin 160 has a role in nuclear transport and Golgi apparatus localization PMID: 12130652
    5. results indicate that GCP16 is the acylated membrane protein, associated with GCP170, and possibly involved in vesicular transport from the Golgi to the cell surface PMID: 14522980
    6. Caspase-resistant GOLGA3 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. PMID: 15829563
    7. golgin-160 assosiates in an isoform-specific manner with the Golgi-associated protein PIST PMID: 15951434
    8. GCP60 interacts preferentially with one of the golgin-160 caspase cleavage fragments (residues 140-311). This strong interaction prevented the golgin-160 fragment from accumulating in the nucleus when this fragment and GCP60 were overexpressed. PMID: 16870622
    9. golgin-160 may promote efficient surface delivery of a subset of cargo molecules PMID: 17118120
    10. nuclear translocation of golgin-160-(140-311) is a highly coordinated event regulated not only by cleavage of the golgin-160 head but also by the oxidation state of GCP60 PMID: 17711851

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  • 亞細(xì)胞定位：
    Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
  • 組織特異性：
    Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4426

    OMIM: 602581

    KEGG: hsa:2802

    STRING: 9606.ENSP00000204726

    UniGene: Hs.507333