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GP5 Antibody

  • 中文名稱：
    GP5兔多克隆抗體
  • 貨號：
    CSB-PA006196
  • 規(guī)格：
    ￥880
  • 圖片：
    • Western Blot analysis of Hela cells using CD42d Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD antigen CD42d
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CD42d.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
  • 基因功能參考文獻(xiàn)：
    1. Raft association and cytoskeletal linkage of the platelet GPIb-IX-V complex are interrelated, and are required for optimal receptor function by attracting signaling proteins and membrane skeletal association allows proteins to move to new locations. PMID: 19874464
    2. Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity. PMID: 11686325
    3. GPV is cleaved upon agonist-induced platelet activation, with ADAM17 as the major enzyme mediating this process PMID: 15691827
  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Platelets and megakaryocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4443

    OMIM: 173511

    KEGG: hsa:2814

    STRING: 9606.ENSP00000319286

    UniGene: Hs.73734