GPR126 Antibody
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中文名稱:GPR126兔多克隆抗體
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貨號(hào):CSB-PA002757
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規(guī)格:¥880
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:adhesion G protein coupled receptor G6 antibody; APG1 antibody; Developmentally regulated G protein coupled receptor antibody; Developmentally regulated G-protein-coupled receptor antibody; dj287g14.2 antibody; DREG antibody; G protein coupled receptor 126 antibody; G-protein coupled receptor 126 antibody; GP126_HUMAN antibody; GPR126 antibody; HBV PreS1 transactivated protein 2 antibody; HBV PreS1-transactivated protein 2 antibody; LCCS9 antibody; OTTHUMP00000017320 antibody; OTTHUMP00000237093 antibody; OTTHUMP00000237094 antibody; OTTHUMP00000237115 antibody; PR126 antibody; Probable G protein coupled receptor 126 [Precursor] antibody; Probable G protein coupled receptor 126 antibody; Probable G-protein coupled receptor 126 [Precursor] antibody; Probable G-protein coupled receptor 126 antibody; PS1TP2 antibody; Vascular inducible G protein coupled receptor antibody; Vascular inducible G protein-coupled receptor antibody; VIGR antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Synthesized peptide derived from the Internal region of Human GPR126.
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:WB, IHC, IF, ELISA
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling. May act as a receptor for PRNP which may promote myelin homeostasis.
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基因功能參考文獻(xiàn):
- The association of a single nucleotide polymorphism in GPR126 with aggressive periodontitis in a Japanese population. The role of GPR126 in maintaining the homeostasis of periodontal ligament tissues. PMID: 27509131
- Together, these data uncover Gpr126 as a genetic cause for the pathogenesis of Adolescent idiopathic scoliosis (AIS) and pectus excavatum in a mouse model. PMID: 25954032
- Genetic variants of GPR126 gene are associated with adolescent idiopathic scoliosis susceptibility in Chinese populations. PMID: 25479386
- Mutations of GPR126 are responsible for severe arthrogryposis multiplex congenita. PMID: 26004201
- GPR126 modulates both physiological and pathological angiogenesis through VEGF signaling PMID: 25217645
- Gpr126 functions in Schwann cells for proper development and myelination through G-protein-signaling pathways. PMID: 24227709
- A single nucleotide polymorphism in the GPR126 gene is associated with increased susceptibility for adolescent idiopathic scoliosis. [Meta-analysis] PMID: 23666238
- Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms. PMID: 21929287
- The PS1TP2 gene was located at 6q24.1, and interacts with leukocyte proteins. PMID: 18304421
- VIGR represents a novel G protein coupled receptors of the adhesion family, which is unique in its long extra-cellular domain. PMID: 15225624
- APG1 formed an alpha-helical structure at the C-terminal site and a positive charge cluster at the N-terminal site. PMID: 17109822
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相關(guān)疾?。?/div>Lethal congenital contracture syndrome 9 (LCCS9)亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein.蛋白家族:G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily組織特異性:Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.數(shù)據(jù)庫鏈接:
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