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GPX8 Antibody, Biotin conjugated

  • 中文名稱：
    GPX8兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA848417LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GPX8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GPX8; UNQ847/PRO1785; Probable glutathione peroxidase 8; GPx-8; GSHPx-8
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Probable glutathione peroxidase 8 protein (41-209AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Study provides evidence that the conserved N-terminal transmembrane domain of GPX8, in addition to its enzymatic activity, is essential for regulating Ca(2+) dynamics revealing a novel level of integration between redox-related proteins and Ca(2+) signaling/homeostasis. PMID: 28129698
    2. GPX8 is transcriptionally regulated by HIFalpha and modulates growth factor signaling in HeLa cells. PMID: 25557012
    3. Along with the induction of GPX8 in ER-stressed cells, these findings question a ubiquitous role of Ero1alpha as a producer of cytoplasmic ROS under ER stress PMID: 24566470
    4. Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. PMID: 23929719
    5. GPx8 labeled as secreted glutathione peroxidase, is actually endoplasmic reticulum-resident protein disulfide isomerase peroxidase PMID: 21215271

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  • 亞細(xì)胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Glutathione peroxidase family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 33100

    KEGG: hsa:493869

    STRING: 9606.ENSP00000423822

    UniGene: Hs.289044