GRM8 Antibody
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中文名稱(chēng):GRM8兔多克隆抗體
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貨號(hào):CSB-PA009035
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:FLJ41058 antibody; GLUR8 antibody; Glutamate receptor metabotropic 8 antibody; GPRC1H antibody; GRM8 antibody; GRM8_HUMAN antibody; Metabotropic glutamate receptor 8 antibody; MGC126724 antibody; mGlu8 antibody; mGluR8 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse,Rat
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免疫原:Synthesized peptide derived from the C-terminal region of Human mGluR-8.
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:WB, IHC, ELISA
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
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基因功能參考文獻(xiàn):
- This study showed that GRM8 was nominally associated (p < 0.05) with both delta measures (energy and intertrial phase coherence). PMID: 27871913
- These results further implicate the role of glutamate receptor genes such as GRM8 in the development of alcohol dependence. PMID: 25978827
- Genome wide association study and meta-analysis results detected rs6951643, a GRM8 genetic variant as suggestive marker for sporadic Creutzfeldt-Jakob disease risk mapping outside the PRNP region. PMID: 25918841
- propose three potential human candidate genes for voluntary physical exercise levels (MC3R, CYP24A1, and GRM8). PMID: 24821406
- The GRM8 gene might play an important role in the pathogenesis of schizophrenia. PMID: 25588301
- Glutamate acts as a partial inverse agonist to metabotropic glutamate receptor with a single amino acid mutation in the transmembrane domain PMID: 23420844
- Eight suggestive significant loci were detected with a series of genes expressed within the inner ear that underlie the auditory function, such as: DCLK1, PTPRD, GRM8, CMIP. PMID: 21493956
- Pias1 binds to and sumoylates metabotropic glutamate receptor 8 PMID: 16144832
- GRM8 genes are likely involved in the pathogenesis of autistic disorder. PMID: 17955477
- Association of suingle nucleotide polymorphisms in GRM8 with theta power of event-related oscillations and alcohol dependence are reported. PMID: 18618593
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亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein.
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蛋白家族:G-protein coupled receptor 3 family
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數(shù)據(jù)庫(kù)鏈接:
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