Gfer Antibody, FITC conjugated
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中文名稱(chēng):Gfer兔多克隆抗體, FITC偶聯(lián)
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貨號(hào):CSB-PA733907HC01RA
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱(chēng):Rabbit anti-Rattus norvegicus (Rat) Gfer Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:Gfer antibody; AlrFAD-linked sulfhydryl oxidase ALR antibody; EC 1.8.3.2 antibody; Augmenter of liver regeneration antibody
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宿主:Rabbit
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反應(yīng)種屬:Rat
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免疫原:Recombinant Rat FAD-linked sulfhydryl oxidase ALR protein (1-198AA)
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免疫原種屬:Rattus norvegicus (Rat)
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標(biāo)記方式:FITC
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克隆類(lèi)型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. May have a function in liver regeneration and spermatogenesis.
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基因功能參考文獻(xiàn):
- our results demonstrate that Growth Factor Erv1-Like gene knock-down, i.e., the lack of Augmenter of Liver Regeneration, modifies the expression of genes involved in cell apoptosis and inhibits early phase of DNA synthesis. PMID: 24880092
- improves hepatocyte survival and promoted liver recovery after transplantation for acute liver failure PMID: 23337881
- ALR may serve as a potential diagnostic marker of hepatocellular stress and/or acute inflammatory conditions. PMID: 23073658
- ALR level in serum may indicate hepatocyte proliferation or liver regeneration. High ALR level in serum in early stage of acute-on-chrinic liver failure may mean a good prognosis. PMID: 22246190
- Loss of augmenter of liver regeneration is associated with renal dysfunction in ischaemia/reperfusion injury. PMID: 20332418
- effectively accelerates kidney recovery after acute renal failure induced by gentamicin; the protective effect is associated with enhanced proliferation of renal tubular cells PMID: 20030531
- crystal structure of ALR has been determined to 1.8 A, and possible physiological roles of ALR are examined PMID: 12717032
- Data show that augmenter of liver regeneration factor (ALR) can promote hepatocyte proliferation induced by Kupffer cells, suggesting that Kupffer cells play a dual role in liver regeneration. PMID: 16937468
- review of the molecular biology of ALR [review] PMID: 16937489
- Demonstrate that Alrp improves SH-SY5Y cells survival in H(2)O(2)-induced apoptosis. PMID: 19629817
- Demonstrate specific G-protein coupled binding of ALR and its function in Kupffer cells and suggest that mediators produced by ALR-stimulated Kupffer cells may elicit physiologically important effects on hepatocytes. PMID: 19859909
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亞細(xì)胞定位:Mitochondrion intermembrane space. Mitochondrion.
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