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HACL1 Antibody

  • 中文名稱：
    HACL1兔多克隆抗體
  • 貨號：
    CSB-PA546627
  • 規(guī)格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Human testis tissue, mouse liver tissue, Hela cells, 293T cells, Primary antibody: CSB-PA546627(HACL1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    HACL1
  • 別名：
    1600020H07Rik antibody; 2 HPCL antibody; 2 hydroxyacyl CoA lyase 1 antibody; 2 hydroxyphytanoyl CoA lyase antibody; 2-HPCL antibody; 2-hydroxyacyl-CoA lyase 1 antibody; 2-hydroxyphytanoyl-CoA lyase antibody; FLJ55041 antibody; Hacl1 antibody; HACL1_HUMAN antibody; HPCL antibody; HPCL2 antibody; HSPC279 antibody; PHYH2 antibody; Phytanoyl CoA 2 hydroxylase 2 antibody; Phytanoyl CoA hydroxylase 2 antibody; Phytanoyl-CoA 2-hydroxylase 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human HACL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產品評價

靶點詳情

  • 功能：
    Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver.
  • 基因功能參考文獻：
    1. Data show that a easy assay for 2-hydroxyacyl-CoA lyase (HACL1) and sphingosine-1-phosphate lyase (SGPL1) activities was developed. PMID: 24323699
    2. Transport of thiamine pyrophosphate into peroxisomes is dependent on HACL1 import, without requirement of a specific solute transporter. PMID: 21708296
    3. 2-hydroxyphytanoyl-CoA lyase has a role in the breakdown of long chain 2-hydroxyfatty acids PMID: 15644336
    4. peroxisomal thiamine-pyrophosphate depending enzyme required for the degradation of phytanic acid, catalyzing the cleavage of 2-hydroxyphytanoyl-CoA lyase into formyl-CoA and pristanal PMID: 10468558
  • 亞細胞定位：
    Peroxisome.
  • 蛋白家族：
    TPP enzyme family
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 17856

    OMIM: 604300

    KEGG: hsa:26061

    STRING: 9606.ENSP00000323811

    UniGene: Hs.63290