HOXB5 Antibody
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中文名稱:HOXB5兔多克隆抗體
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貨號(hào):CSB-PA002960
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規(guī)格:¥880
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:HOXB5
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別名:HGNC:5116 antibody; HHO.C10 antibody; Homeo box 2A antibody; Homeo box B5 antibody; Homeobox 2A antibody; Homeobox B5 antibody; Homeobox protein HHO.C10 antibody; Homeobox protein Hox B5 antibody; Homeobox protein Hox-2A antibody; Homeobox protein Hox-B5 antibody; Homeobox protein HoxB5 antibody; Homeobox protein Hu-1 antibody; Homeobox2A antibody; HomeoboxB5 antibody; HOX 2 antibody; Hox 2.1 antibody; HOX 2A antibody; HOX B5 antibody; HOX2 antibody; Hox2.1 antibody; Hox2.1, mouse, homolog of antibody; HOX2A antibody; HOXB 5 antibody; Hoxb5 antibody; HU 1 antibody; HU1 antibody; HXB5_HUMAN antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse
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免疫原:Synthesized peptide derived from the Internal region of Human HoxB5.
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:WB, ELISA
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
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基因功能參考文獻(xiàn):
- for the first time we have shown that knockdown of HOXB5 significantly inhibited non-small cell lung cancer cell proliferation, invasion, metastasis, and epithelial-mesenchymal transformation, partly through the Wnt/beta-catenin signaling pathway PMID: 28337958
- Taken together, our results for the first time suggested that miR-455-3p was downregulated in NSCLC and was correlated with the poor prognosis of NSCLC patients. Also, miR-455-3p functions as tumor suppressor by directly targeting HOXB5 in NSCLC progression and may be used as a potential target for NSCLC treatment. PMID: 29170127
- HOXB5 acts as a positive modulator by promoting cell proliferative response and invasiveness in ER-positive breast cancer. PMID: 25999793
- HOXB5 may be an important regulator of the Wnt/beta-catenin signalling pathway, thereby contributing to gastric cancer progression and metastasis. PMID: 26467157
- Roles of Hoxb5 in the development of vagal and trunk neural crest cells. PMID: 25703667
- Overexpression of HoxB5 enhances blood vessel perfusion in vivo by up-regulation of MCP-1 and IL-6 as well as in enhanced leucocyte infiltration and blood vessel remodelling. PMID: 24189625
- HOXB5 and HOXB8 are frequently expressed in ovarian serous carcinoma, with anatomic site-related differences for cytoplasmic staining. HOXB5 may be affected by chemotherapy in effusions. PMID: 23438671
- The findings for HOXB5 and PHOX2B provide supportive evidence that genes regulating ENCC proliferation, migration and differentiation could be risk factors for Hirschsprung's disease PMID: 22648184
- A miRNA 7-binding single nucleotide polymorphism (1010A/G) located within 3'-UTR of HOXB5 is associated with gene expression and may be a promising prognostic factor for bladder cancer. PMID: 22768238
- HOXB5, HOXB6, and HOXB7 are activated in Barrett esophagus, and the midcluster HOXB gene signature in BE most resembled the colon rather than other GI epithelia. PMID: 22603795
- Single nucleotide polymorphism in HOXB5 gene is associated with childhood obesity. PMID: 22484627
- results support that expression of HOX genes is associated with oral squamous cell carcinoma; over 90% of OSCC samples presented HOXB5 expression versus 60% of non-tumor tissues, it can be suggested that HOXB5 may be related to the malignant phenotypes. PMID: 21552713
- Data show that human HOXB5 binds to the promoter region 5' upstream of the binding site of NKX2-1 and regulates RET expression. PMID: 21677782
- HoxB5 is necessary and sufficient to activate the cell-intrinsic events that regulate the differentiation of angioblasts and mature endothelial cells from their mesoderm-derived precursors PMID: 12897140
- The expression pattern of HOXB5 correlated with the migration and differentiation of neural crest cells. PMID: 12950074
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亞細(xì)胞定位:Nucleus.
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蛋白家族:Antp homeobox family
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組織特異性:Spinal cord.
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