HSD3B7 Antibody
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中文名稱:HSD3B7兔多克隆抗體
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貨號:CSB-PA861999LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Western Blot
Positive WB detected in: Mouse liver tissue, Mouse kidney tissue
All lanes: HSD3B7 antibody at 3.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 42, 22 kDa
Observed band size: 42 kDa -
Immunofluorescent analysis of HepG2 cells using CSB-PA861999LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) HSD3B7 Polyclonal antibody
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Uniprot No.:
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基因名:HSD3B7
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別名:HSD3B7; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5-C27 steroid oxidoreductase; C(27 3-beta-HSD; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase
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宿主:Rabbit
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反應(yīng)種屬:Human, Mouse
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免疫原:Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 protein (131-197AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,HSD3B7 Antibody (CSB-PA861999LA01HU),的標(biāo)記方式是Non-conjugated。對于HSD3B7 Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB, IF
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 IF 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis. Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
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基因功能參考文獻(xiàn):
- Novel Mutations in the 3beta-hydroxy-5-C27-steroid Dehydrogenase Gene (HSD3B7) in a Patient with Neonatal Cholestasis. PMID: 26712441
- Expression of steroid sulfated transporters and 3beta-HSD activity in endometrium of polycystic ovary syndrome PMID: 26450365
- Homozygosity mapping identifies a bile acid biosynthetic defect (3beta-HSD deficiency due to a frameshift mutation in HSD3B7) in an adult with cirrhosis of unknown etiology. PMID: 22095780
- Mutations in the HSD3B7 gene account for autosomal recessive neonatal cholestasis caused by 3[beta]-hydroxy-[DELTA]5-C27-steroid dehydrogenase/isomerase deficiency. PMID: 20531254
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相關(guān)疾病:Congenital bile acid synthesis defect 1 (CBAS1)
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亞細(xì)胞定位:Endoplasmic reticulum membrane; Multi-pass membrane protein.
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蛋白家族:3-beta-HSD family
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數(shù)據(jù)庫鏈接:
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